SAB4300231

Anti-phospho-GAB1 (pTyr⁶²⁷) antibody produced in rabbit

affinity isolated antibody

• Synonym(s): Anti-GRB2-associated binding protein 1 antibody produced in rabbit
• UNSPSC Code: 12352203
• NACRES: NA.41

Properties

• biological source: rabbit
• conjugate: unconjugated
• antibody form: affinity isolated antibody
• antibody product type: primary antibodies
• clone: polyclonal
• form: buffered aqueous solution
• mol wt: ~110 kDa
• species reactivity: mouse, human
• concentration: 1 mg/mL
• technique(s): indirect immunofluorescence: 1:100-1:200; western blot: 1:500-1:1000
• isotype: IgG
• immunogen sequence: (V-E-YP-L-D)
• NCBI accession no.: NP_002030.2
• UniProt accession no.: Q13480
• shipped in: wet ice
• storage temp.: −20°C
• target post-translational modification: phosphorylation (pTyr627)
• Gene Information: human ... GAB1(2549)

Description

Immunogen

Peptide sequence around phosphorylation site of tyrosine 627 (V-E-Y(p)-L-D), according to the protein GAB1.

Features and Benefits

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Target description

The protein encoded by Gab1 is a member of the IRS1-like multisubstrate docking protein family. It is an important mediator of branching tubulogenesis and plays a central role in cellular growth response, transformation and apoptosis. Two transcript variants encoding different isoforms have been found for this gene.

Physical form

Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol

Safety Information

• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 1
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable