SAB4100383

Monoclonal Anti-TMOD1 antibody produced in mouse

clone TMOD1-A328, culture supernatant

• Synonym(s): Anti-D9S57E, Anti-ETMOD, Anti-TMOD, Anti-tropomodulin 1
• UNSPSC Code: 12352203
• NACRES: NA.41

Properties

• conjugate: unconjugated
• antibody form: culture supernatant
• antibody product type: primary antibodies
• clone: TMOD1-A328, monoclonal
• form: aqueous solution
• mol wt: antigen predicted mol wt 40.4 kDa
• species reactivity: human
• technique(s): western blot: suitable
• isotype: IgG2b
• UniProt accession no.: P28289
• shipped in: dry ice
• storage temp.: −20°C
• Gene Information: human ... TMOD1(7111)

Description

General description

Tropomodulin 1 (TMOD1) is an actin-capping protein, which is expressed in the cardiac muscle and in slow-twitch muscle fibers. It possesses two actin- and two tropomyosin (TM)-binding regions. The gene encoding this protein is localized on human chromosome 9q.[1][2][3]

Immunogen

TMOD1 purified recombinant protein

Biochem/physiol Actions

Tropomodulin 1 (TMOD1) prevents the elongation and depolymerization of actin filaments by binding to the slowly growing pointed end of the actin filament. It has been associated with triple-negative breast cancers (TNBC). TMOD1 may act as a stabilizer of β-catenin.[4][1]

Physical form

Solution in Dulbecco′s Modified Eagle′s Medium with 10% fetal calf serum and 15 mM sodium azide.

Safety Information

• Storage Class Code: 12 - Non Combustible Liquids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable