Skip to Content
Merck
All Photos(1)

Key Documents

L6420

Sigma-Aldrich

Luteinizing Hormone from human pituitary

≥8,500 IU/mg

Synonym(s):

ICSH, LH, PLH

Sign Into View Organizational & Contract Pricing
All Photos(1)

About This Item

CAS Number:
39341-83-8
EC Number:
254-420-6
MDL number:
MFCD03846454
UNSPSC Code:
12352202
NACRES:
NA.77
Pricing and availability is not currently available.

Quality Level

200

specific activity

≥8,500 IU/mg

shipped in

dry ice

storage temp.

−20°C

Looking for similar products? Visit Product Comparison Guide

Related Categories

Biochem/physiol Actions

Two-chain glycoprotein hormone; the α-chain is identical to that of chorionic gonadotropin, TSH, and FSH, while biological specificity is attributed to the distinct β-chain. Induces ovulation, spermatogenesis, and synthesis of steroid sex hormones.
Two-chain glycoprotein hormone; the α-chain is identical to that of chorionic gonadotropin, TSH, and FSH, while biological specificity is attributed to the distinct β-chain. Induces ovulation, spermatogenesis, and synthesis of steroid sex hormones. Activity is mediated through a trans-membrane LH/chorionic gonadotropin receptor that is a member of the G-protein coupled receptor (GPCR) family.

Physical form

Lyophilized from 50 mM ammonium bicarbonate

related product

Product No.
Description
Pricing

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
0000417715
0000417715
0000413542
0000413542
0000405254

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Mitsuru Komeya et al.
Scientific reports, 6, 21472-21472 (2016-02-20)
In contrast to cell cultures, particularly to cell lines, tissues or organs removed from the body cannot be maintained for long in any culture conditions. Although it is apparent that in vivo regional homeostasis is facilitated by the microvascular system
Hanyong Jin et al.
Biochemical and biophysical research communications, 482(4), 877-882 (2016-11-29)
Pituitary gonadotropins are key hormones that orchestrate the growth and development of ovarian follicles. However, limited information is available on intra-ovarian factors that mediate the actions of gonadotropins. In this study, we identified that the early growth response 2 gene
Cheng Peng et al.
General and comparative endocrinology, 267, 90-97 (2018-06-19)
Luteinizing hormone receptor (LHR) plays a critical role in reproduction by mediating LH signaling in the gonad. In this study, we cloned a novel lhr gene from the orange-spotted grouper, named glhr2. The cloned complete open reading frame sequence of
Affiefa Yawer et al.
Toxicology and applied pharmacology, 404, 115177-115177 (2020-08-03)
A decline in male fertility possibly caused by environmental contaminants, namely endocrine-disrupting chemicals (EDCs), is a topic of public concern and scientific interest. This study addresses a specific role of testicular gap junctional intercellular communication (GJIC) between adjacent prepubertal Leydig
Xuerui Yao et al.
Theriogenology, 151, 66-73 (2020-04-21)
Zearalenone (ZEA), which is produced by several fusarium mycotoxins, is found in animal feed and food products, and can exert estrogen-like activity. Melatonin (MT) is emerging as a supplement that can fight the toxic effects of mycotoxins. With a variety
View All Related Papers

Questions

1–2 of 2 Questions  

  1. What volumen of the buffer should be added to dilute the product?

    1 answer

    1. For a stock solution, hormones should be reconstituted to ≥1 mg/ml in the presence of a protease-free carrier (0.1-1% ovalbumin, BSA, or gelatin) and a suitable antimicrobial agent. The following general guidelines may be useful:

      1. Ovalbumin is generally used when assaying for gonadotropin;
      2. If BSA is used, it must be free of gonadotropins and proteases (either crystalline or RIA grade is generally satisfactory);
      3. Heat gelatin solutions to 60°C for maximum solubility (1% gelatin for ELISAs, 0.1% for solid phase assays);
      4. For the pituitary hormones hFSH, hLH, hPRL, and hTSH, the recommended dilution buffer is 10 mM Sodium Phosphate, 150 mM Sodium Chloride, 1 mg/ml BSA, 0.1% Sodium Azide, pH 7.4 is generally satisfactory for hFSH, hLH, hPRL, and hTSH.
      5. For hCG and hGH, the recommended dilution buffer is 100 mM Tris, 1 mg/ml BSA, 0.05% Sodium Azide, pH 8.0 is generally satisfactory for hCG and hGH.

      Helpful?

  2. How to dilute the LH L6420

    1 answer

    1. It is recommended to dilute Product LH L6420 in a buffer consisting of 10 mM Sodium Phosphate, 150 mM Sodium Chloride, 1 mg/ml BSA, 0.1% Sodium Azide (optional), pH 7.4.

      Helpful?

Reviews

No rating value

Active Filters

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service