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I7013

Sigma-Aldrich

Imidazole-4-acetic acid sodium salt

Synonym(s):

I4AA

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About This Item

Empirical Formula (Hill Notation):
C5H5N2NaO2
CAS Number:
56368-58-2
Molecular Weight:
148.10
MDL number:
MFCD00005204
UNSPSC Code:
12352200
PubChem Substance ID:
24896104
Pricing and availability is not currently available.

storage temp.

2-8°C

SMILES string

[Na+].[O-]C(=O)Cc1c[nH]cn1

InChI

1S/C5H6N2O2.Na/c8-5(9)1-4-2-6-3-7-4;/h2-3H,1H2,(H,6,7)(H,8,9);/q;+1/p-1

InChI key

JDDRCOTZMQIPOQ-UHFFFAOYSA-M

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Biochem/physiol Actions

Competitive antagonist at GABAC receptors.

Features and Benefits

This compound is a featured product for Neuroscience research. Click here to discover more featured Neuroscience products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H315,H319,H335

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

13 - Non Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
110K1583
057K1839
057K1517
116K1540
076K1733

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David I Pattison et al.
Biochemistry, 44(19), 7378-7387 (2005-05-11)
Hypochlorous acid (HOCl) is a powerful oxidant generated from H(2)O(2) and chloride ions by the heme enzyme myeloperoxidase (MPO) released from activated leukocytes. In addition to its potent antibacterial effects, excessive HOCl production can lead to host tissue damage, with
Karin N Barnouin et al.
Proteomics, 5(17), 4376-4388 (2005-11-19)
IMAC can be used to selectively enrich phosphopeptides from complex peptide mixtures, but co-retention of acidic peptides together with the failure to retain some phosphopeptides restricts the general utility of the method. In this study Fe(III)-IMAC was qualitatively and quantitatively
Theoretical studies of IMAC interfacial phenomena for the production of protein C.
E Eileen Thiessen et al.
Advances in experimental medicine and biology, 540, 183-190 (2004-06-04)
Greg T Cantin et al.
Analytical chemistry, 79(12), 4666-4673 (2007-05-26)
An automated online multidimensional liquid chromatography system coupled to ESI-based tandem mass spectrometry was used to assess the effectiveness of TiO2 in the enrichment of phosphopeptides from tryptic digests of protein mixtures. By monitoring the enrichment of phosphopeptides, an optimized
Jan Sedzik et al.
Protein expression and purification, 26(3), 368-377 (2002-12-04)
The preparation of a pure and homogeneous protein sample at proper concentration is a prerequisite for success when attempting their crystallization for structural determination. The detergents suitable for solubilization particularly of membrane proteins are not always the best for crystallization.
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