H7629

γ-Butyrolactone

≥99% (GC)

• Synonym(s): γ-Hydroxybutyric acid lactone, 4-Hydroxybutyric acid lactone, GBL
• Empirical Formula (Hill Notation): C₄H₆O₂
• CAS Number: 96-48-0
• Molecular Weight: 86.09
• Beilstein: 105248
• EC Number: 202-509-5
• MDL number: MFCD00005386
• UNSPSC Code: 12352100
• PubChem Substance ID: 329815243

Properties

• vapor density: 3 (vs air)
• vapor pressure: 1.5 mmHg ( 20 °C)
• Assay: ≥99% (GC)
• autoignition temp.: 851 °F
• expl. lim.: 16 %
• refractive index: n20/D 1.436 (lit.)
• bp: 204-205 °C (lit.)
• mp: −45 °C (lit.)
• density: 1.12 g/mL at 25 °C (lit.)
• storage temp.: 2-8°C
• SMILES string: O=C1CCCO1
• InChI: 1S/C4H6O2/c5-4-2-1-3-6-4/h1-3H2
• InChI key: YEJRWHAVMIAJKC-UHFFFAOYSA-N

Description

Biochem/physiol Actions

Precursor of γ-hydroxybutyric acid (GHB). It blocks dopamine release by blocking impulse flow in dopaminergic neurons. Pretreatment with γ-butyrolactone allows detection of autoreceptor-induced dopamine release.

Safety Information

• Pictograms: GHS05,GHS07
• Signal Word: Danger
• Hazard Statements: H302,H318,H336
• Precautionary Statements: P261 - P264 - P271 - P280 - P301 + P312 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 4 Oral - Eye Dam. 1 - STOT SE 3
• Target Organs: Central nervous system
• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 1
• Flash Point(F): 208.4 °F - closed cup
• Flash Point(C): 98 °C - closed cup
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves