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G2386

Sigma-Aldrich

N-Glutaryl-Gly-Arg-7-amido-4-methylcoumarin hydrochloride

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About This Item

Empirical Formula (Hill Notation):
C23H30N6O7 · HCl
CAS Number:
103213-40-7
Molecular Weight:
538.98
MDL number:
MFCD00058182
UNSPSC Code:
12352204
PubChem Substance ID:
24895095

storage temp.

−20°C

SMILES string

Cl.CC1=CC(=O)Oc2cc(NC(=O)C(CCCNC(N)=N)NC(=O)CNC(=O)CCCC(O)=O)ccc12

Substrates

A fluorogenic substrate for urokinase.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
SLBD2411V
094K1134
129H1565
075H0216
066H1195

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T Morita et al.
Journal of biochemistry, 82(5), 1495-1498 (1977-11-01)
Twenty peptide-4-methylcoumarin amides (MCA) were newly synthesized and tested as possible substrates for alpha-thrombin, factor Xa, kallikreins, urokinase, and plasmin. These fluorogenic peptides contained arginine-MCA as the carboxyl-terminus. Release of 7-amino-4-methylcoumarin was determined fluorometrically. Of these peptides, the following were
Assay of coagulation proteases using peptide chromogenic and fluorogenic substrates.
R Lottenberg et al.
Methods in enzymology, 80 Pt C, 341-361 (1981-01-01)

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