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EMU065561

Sigma-Aldrich

MISSION® esiRNA

targeting mouse Dynll1

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About This Item

UNSPSC Code:
41105324
NACRES:
NA.51

description

Powered by Eupheria Biotech

product line

MISSION®

form

lyophilized powder

esiRNA cDNA target sequence

CCTAGGAGCTCGCAGCAGCCGGCTGGCCTCTGCTCCACGGTAACCATGTGCGACCGGAAGGCGGTGATCAAAAATGCAGACATGTCGGAAGAGATGCAACAGGACTCGGTGGAGTGCGCTACCCAGGCGTTGGAGAAGTACAACATCGAGAAGGATATTGCGGCCCATATCAAGAAGGAGTTTGACAAGAAGTACAACCCTACCTGGCACTGCATTGTGGGCCGAAACTTCGGTAGTTATGTGGCACATGAAACCAAACACTTCATCTACTTCTACCTGGGTCAGGTGGCCATTCTTCTGTTCAAATCTGGTTAAAAGCATGGACTGTGCCAAACACCCAGTGATCCATCCAAAAACAAGGACTGCATCCAAATTCCAAATACCAGAGACTGAATCTTCAGCCTTGCTAAGGGA

Ensembl | mouse accession no.

ENSMUSG00000009013

NCBI accession no.

NP_062656

shipped in

ambient

storage temp.

−20°C

Gene Information

mouse ... DYNLL1(56455) , Dynll1(56455)

General description

MISSION® esiRNA are endoribonuclease prepared siRNA. They are a heterogeneous mixture of siRNA that all target the same mRNA sequence. These multiple silencing triggers lead to highly-specific and effective gene silencing.

For additional details as well as to view all available esiRNA options, please visit SigmaAldrich.com/esiRNA.

Legal Information

MISSION is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class Code

10 - Combustible liquids

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

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Yi-Ping Shih et al.
Biochimica et biophysica acta, 1853(12), 3258-3265 (2015-10-03)
DLC1 is a RhoGAP-containing tumor suppressor and many of DLC1's functions are absolutely dependent on its RhoGAP activity. Through its RhoGAP domain, DLC1 inhibits the activity of RhoA GTPase, which regulates actin cytoskeleton networks and dis/assembly of focal adhesions. Tensin1

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