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EHU024111

Sigma-Aldrich

MISSION® esiRNA

targeting human SNX27

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About This Item

UNSPSC Code:
41105324
NACRES:
NA.51

description

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Quality Level

product line

MISSION®

form

lyophilized powder

esiRNA cDNA target sequence

GGGAAGTGGCCATTTTCATTATCAGAACAACAATTAGATGCCCGACGTCGGGGATTGGAAGAATATCTAGAAAAAGTGTGTTCAATACGAGTAATTGGTGAGAGTGACATCATGCAGGAATTCCTATCAGAATCCGATGAGAACTACAATGGTGTGTCCGACGTAGAGCTGAGAGTAGCATTACCAGATGGAACAACGGTTACAGTCAGGGTTAAAAAGAACAGTACTACAGACCAAGTATATCAGGCTATCGCAGCAAAGGTTGGCATGGACAGTACGACAGTGAATTACTTTGCCTTATTTGAAGTGATCAGTCACTCCTTTGTACGTAAATTGGCACCTAATGAGTTTCCTCACAAACTCTACATTCAGAATTATACATCAGCTGTGCCAGGCACCTGCTTGACCATTCGAAAGTG

Ensembl | human accession no.

NCBI accession no.

shipped in

ambient

storage temp.

−20°C

Gene Information

General description

MISSION® esiRNA are endoribonuclease prepared siRNA. They are a heterogeneous mixture of siRNA that all target the same mRNA sequence. These multiple silencing triggers lead to highly-specific and effective gene silencing.

For additional details as well as to view all available esiRNA options, please visit SigmaAldrich.com/esiRNA.

Legal Information

MISSION is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class Code

10 - Combustible liquids

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

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Ketaki Ganti et al.
PLoS pathogens, 12(9), e1005854-e1005854 (2016-09-21)
A subset of high-risk Human Papillomaviruses (HPVs) are the causative agents of a large number of human cancers, of which cervical is the most common. Two viral oncoproteins, E6 and E7, contribute directly towards the development and maintenance of malignancy.
Ian J McGough et al.
Nature communications, 9(1), 3737-3737 (2018-09-15)
Wntless transports Wnt morphogens to the cell surface and is required for Wnt secretion and morphogenic gradients formation. Recycling of endocytosed Wntless requires the sorting nexin-3 (SNX3)-retromer-dependent endosome-to-Golgi transport pathway. Here we demonstrate the essential role of SNX3-retromer assembly for

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