Equimolar concentrations of [4-14C]oestriol and [6,9-3H]oestriol 16 alpha-monoglucuronide were simultaneously perfused through isolated rat livers. Oestriol was hydroxylated to 2-hydroxyoestriol and 6 xi-hydroxyoestriol; 2-hydroxyoestriol was further methylated to 2-methoxyoestriol. Oxidoreduction of oestriol led to the formation of 16 alpha-hydroxyoestrone, 16-0xooestradio-17
Zeitschrift fur Geburtshilfe und Perinatologie, 185(5), 284-287 (1981-10-01)
A method based on the inhibition of hemagglutination for the determination of estriol-16-alpha-glucuronide is compared to the method of Kober and Ittrich. A sufficient degree of correlation (p less than 0.001) is found, when the daily estrogen production (Kober-Ittrich) in
The Journal of pharmacology and experimental therapeutics, 229(1), 175-181 (1984-04-01)
The uptake of estradiol-17 beta(beta-D-glucuronide) (E(2)17G), estriol-16 alpha(beta-D-glucuronide (E(3)16G), estradiol-17 beta-3-(beta-D-glucuronide) (E(2)3G) and taurocholate (TC) into hepatocytes isolated from male and female rats was examined and found to be linear for at least 75 sec and to exhibit Michaelis-Menten kinetics.
Use of [125I]-iodohistamine-labelled steroid derivatives as radioligands for radioimmunoassay of natural and synthetic steroids.
F Z Stanczyk et al.
Journal of steroid biochemistry, 14(1), 53-62 (1981-01-01)
Biological research in pregnancy and perinatology, 5(2), 68-73 (1984-01-01)
The maternal peripheral serum level of estradiol-17 beta (E2), which reaches a peak a few weeks before delivery, may play a role in initiating delivery. In this study, the steroidal activity regulated by both the production and conjugation was estimated
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