A series of lanostane-type triterpenoids, identified as ganoderma alcohols and ganoderma acids, were isolated from the fruiting body of Ganoderma lingzhi. Some of these compounds were confirmed as active inhibitors of the in vitro human recombinant aldose reductase. This paper
Human gene therapy. Clinical development, 24(3), 127-133 (2013-09-12)
A biodistribution and toxicology study was performed to test the acute toxicities of intradiaphragmatic injection of a recombinant adeno-associated virus (rAAV) 2/1-human acid alpha-Glucosidase (hGAA) driven by a cytomegalovirus (CMV) promoter (rAAV1-CMV-hGAA) in New Zealand white rabbits and in the
Molecular genetics and metabolism, 110(3), 287-289 (2013-09-10)
Late-onset Pompe disease is a rare, but potentially treatable metabolic myopathy, and therefore should not be overlooked. However, it is not unusual that patients go undiagnosed for many years. We hypothesized that patients with late-onset Pompe disease may have been
Jiaogulan tea has been commercialised globally. This study investigated the chemical components and health properties of a new jiaogulan genotype, tetraploid Gynostemma pentaphyllum. Two new saponins, (23S)-21β-O-methyl-3β,20ξ-dihydroxy-12-oxo-21,23-epoxydammar-24-ene-3-O-[α-L-rhamnopyranosyl(1→2)][β-D-glucopyranosyl(1→3)]-α-L-arabinopyranoside (4) and 23β-H-3β,20ξ-dihydroxy-19-oxo-21,23-epoxydammar-24-ene-3-O-[α-L-rhamnopyranosyl(1→2)][β-D-xylopyranosyl(1→3)]-α-L-arabinopyranoside (5), together with one lactone, 3,5-dihydroxyfuran-2(5H)-one (1), and two flavonoids
The Biochemical journal, 173(2), 553-563 (1978-08-01)
Maltase-glucoamylase, a microvillous membrane ectoenzyme, was solubilized from rat intestinal mucosa by digestion with papain and subsequently purified to homogeneity with an overall yield of 10--20%. An antibody to the purified enzyme formed a single precipitin line in immunodiffusion experiments
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