Skip to Content
Merck
All Photos(1)

Documents

3015

Sigma-Aldrich

Transcreener® AMP2/GMP2 FP Assay

Sign Into View Organizational & Contract Pricing


About This Item

UNSPSC Code:
41122100
NACRES:
NA.84

shipped in

dry ice

storage temp.

−20°C

General description

The Transcreener® AMP2/GMP2 FP Assay is a universal biochemical HTS assay for enzymes that produce AMP or GMP, including ubiquitin, SUMO, nucleic acid and protein ligases, phosphodiesterases (PDEs), and synthetases. Enzyme activity is signaled by a decrease in fluorescence polarization as the bound tracer is displaced from the Transcreener® AMP2/GMP2 Antibody. The assay is a simple single step mix-and-read format enabling the use of unmodified native substrate concentrations of 1 – 1000 μM. The assay provides excellent signal at low substrate conversion, with a Z′ =0.7 and =100 millipolarization shift (mP) under normal reaction conditions.

View full Transcreener® product list

Quantity

3015-1K = 1,000 assay, 384-well
3015-10K = 10,000 assay, 384-well

Physical form

Kit with buffered aqueous solutions

Legal Information

Transcreener is a registered trademark of BellBrook Labs

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

N García-Romero et al.
Journal of translational medicine, 17(1), 75-75 (2019-03-16)
Extracellular vesicles (EVs) are small membrane-bound vesicles which play an important role in cell-to-cell communication. Their molecular cargo analysis is presented as a new source for biomarker detection, and it might provide an alternative to traditional solid biopsies. However, the

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service