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92614

Supelco

4-Nitro-7-piperazinobenzofurazan

for HPLC derivatization, LiChropur™, ≥99.0%

Synonym(s):

4-Nitro-7-(1-piperazinyl)-2,1,3-benzoxadiazole

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About This Item

Empirical Formula (Hill Notation):
C10H11N5O3
CAS Number:
139332-66-4
Molecular Weight:
249.23
Beilstein:
7936339
MDL number:
MFCD00191507
UNSPSC Code:
12000000
PubChem Substance ID:
329770152
NACRES:
NA.22

grade

for HPLC derivatization

Quality Level

100

Assay

≥99.0% (HPLC)
≥99.0%

form

powder

quality

LiChropur™

technique(s)

HPLC: suitable

fluorescence

λex 395 nm; λem 561 nm in acetone

SMILES string

[O-][N+](=O)c1ccc(N2CCNCC2)c3nonc13

InChI

1S/C10H11N5O3/c16-15(17)8-2-1-7(9-10(8)13-18-12-9)14-5-3-11-4-6-14/h1-2,11H,3-6H2

InChI key

MVLWYDGJBGPXOL-UHFFFAOYSA-N

Application

suitable as derivatizing reagent for isocyanate

Other Notes

Derivatizing agent for the determination of mono- & diisocyanates by LC and MS, UV or fluorescent detection

Recommended products

Discover LiChropur reagents ideal for HPLC or LC-MS analysis

Legal Information

LiChropur is a trademark of Merck KGaA, Darmstadt, Germany

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H302,H315,H319,H335

Hazard Classifications

Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
BCCD7196
BCBZ6419
BCBL8165V
BCBD8322V
1417108

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Chia-Yu Lin et al.
PloS one, 15(10), e0241053-e0241053 (2020-10-27)
The relationship between methylglyoxal (MGO) and D-lactate during saikosaponin C (SSC) treatment of mice with accelerated nephrotoxic serum (NTS) nephritis was investigated. NTS nephritis was induced by administration of anti-basement membrane antibodies to C57BL/6 mice and three dosages of SSC
Hartmut Henneken et al.
Journal of environmental monitoring : JEM, 5(1), 100-105 (2003-03-07)
A diffusive sampling method for the determination of methyl isocyanate (MIC) in air is introduced. MIC is collected using a glass fiber filter impregnated with 4-nitro-7-piperazinobenzo-2-oxa-1,3-diazole (NBDPZ). The urea derivative formed is desorbed from the filter with acetonitrile and analyzed
Shih-Ming Chen et al.
PloS one, 15(7), e0235849-e0235849 (2020-07-11)
Nephrotoxicity severely limits the chemotherapeutic efficacy of cisplatin (CDDP). Oxidative stress is associated with CDDP-induced acute kidney injury (AKI). Methylglyoxal (MG) forms advanced glycation end products that elevate oxidative stress. We aimed to explore the role of MG and its
Yu-Shen Huang et al.
Scientific reports, 8(1), 14587-14587 (2018-10-03)
Chronic kidney disease is a worldwide problem, and Pb contamination is a potential risk factor. Since current biomarkers are not sensitive for the diagnosis of Pb-induced nephrotoxicity, novel biomarkers are needed. Metformin has both hypoglycaemic effects and reno-protection ability. However
Martin Vogel et al.
Analytical chemistry, 74(24), 6418-6426 (2003-01-04)
4-Nitro-7-piperazino-2,1,3-benzoxadiazole (NBDPZ) is presented as a new reagent for the determination of mono- and diisocyanates in air samples. NBDPZ readily reacts with the airborne analytes, thus yielding the corresponding urea derivatives, which are subsequently separated by means of reversed-phase liquid

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