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Sigma-Aldrich

Reagent Alcohol

anhydrous, contains 5% isopropyl alcohol and 5% methyl alcohol as denaturant

Synonym(s):

Ethyl alcohol, Reagent alcohol, Ethanol, RGA, denatured alcohol

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About This Item

CAS Number:
MDL number:
UNSPSC Code:
15101802
PubChem Substance ID:
NACRES:
NA.21

product name

Reagent Alcohol, anhydrous, ≤0.005% water

grade

anhydrous

Quality Level

vapor density

1.59 (vs air)

form

liquid

contains

5% isopropyl alcohol as denaturant
5% methyl alcohol as denaturant

expl. lim.

3.1-27.7 % (lit.)

concentration

100%

impurities

≤0.005% water

evapn. residue

≤0.0005%

bp

78 °C (lit.)

mp

−130 °C

InChI

1S/C2H6O/c1-2-3/h3H,2H2,1H3

InChI key

LFQSCWFLJHTTHZ-UHFFFAOYSA-N

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General description

Reagent alcohol (denatured alcohol) is ethanol that has been denatured by adding additives like methanol and isopropyl alcohol. The addition of these toxic additives makes it non-consumable. It is a constituent of hairspray, spray disinfectants and cosmetics. It is employed in histological and cytological procedures such as staining, slide preparation and also as a fixative. A study reports the use of reagent alcohol as a solvent for the preservation of euthanized sea cucumbers. This is an anhydrous grade solvent with extremely low water content and residue levels making it highly useful for processes that require very low water levels.

Application


  • Microfluidically Assisted Synthesis of Calcium Carbonate Submicron Particles with Improved Loading Properties: Research on microfluidically synthesized calcium carbonate submicron particles shows enhanced loading properties, offering potential advancements in drug delivery systems and other nanotechnology applications (Ermakov AV, et al., 2023).

  • Recent Developments in CaCO3 Nano-Drug Delivery Systems: Advancing Biomedicine in Tumor Diagnosis and Treatment: A review focusing on recent advancements in the development of calcium carbonate-based nano-drug delivery systems, which have significant potential to improve tumor diagnosis and therapy (Lin C, et al., 2024).


Components

95 parts of specially denatured ethyl alcohol 3A, 200 proof, with 5 parts of isopropyl alcohol. Final concentrations are ~ 90% ethanol, ~ 5% methanol and ~ 5% isopropanol.

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Description
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Signal Word

Danger

Hazard Statements

Hazard Classifications

Eye Irrit. 2 - Flam. Liq. 2 - STOT SE 2

Target Organs

Eyes,Central nervous system

Storage Class Code

3 - Flammable liquids

WGK

WGK 2

Flash Point(F)

48.2 °F - closed cup

Flash Point(C)

9 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Recommendations on the use of alcohols for preservation of ant specimens (Hymenoptera, Formicidae).
King JR and Porter SD.
Insectes Sociaux, 51(2), 197-202 (2004)
The uptake of dissolved organic material by the sea cucumber Parastichopus californicus (Stimpson) and its potential role in visceral regeneration.
Brothers CJ, et al.
Journal of Experimental Marine Biology and Ecology, 469, 69-75 (2015)
Rocio Gómez-Cansino et al.
Evidence-based complementary and alternative medicine : eCAM, 2015, 183036-183036 (2015-05-20)
The extracts of 14 Julianaceae and 5 Clusiaceae species growing in Mexico were tested in vitro (50 µg/mL) against Mycobacterium tuberculosis H37Rv and HIV reverse transcriptase (HIV-RT). The Julianaceae bark and leaf extracts inhibited M. tuberculosis (>84.67%) and HIV-RT (<49.89%). The
Surrogate alcohol: what do we know and where do we go?
Lachenmeier DW, et al.
Alcoholism, Clinical and Experimental Research, 31(10), 1613-1624 (2007)
Zeljka Korade et al.
Biological psychiatry, 75(3), 215-222 (2013-07-31)
Smith-Lemli-Opitz syndrome (SLOS) is an inborn error of cholesterol biosynthesis characterized by diminished cholesterol and increased 7-dehydrocholesterol (7-DHC) levels. 7-Dehydrocholesterol is highly reactive, giving rise to biologically active oxysterols. 7-DHC-derived oxysterols were measured in fibroblasts from SLOS patients and an

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