131105
3,6-Diaminoacridine hydrochloride
Dye content 95 %
Synonym(s):
Proflavine hydrochloride, Proflavine monohydrochloride
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About This Item
Empirical Formula (Hill Notation):
C13H11N3 · HCl
CAS Number:
Molecular Weight:
245.71
EC Number:
MDL number:
UNSPSC Code:
12171500
PubChem Substance ID:
NACRES:
NA.47
Recommended Products
Assay
94.0% (HPLC)
form
powder
composition
Dye content, 95%
mp
270 °C (dec.) (lit.)
solubility
H2O: 1 mg/mL, clear
λmax
456 nm
ε (extinction coefficient)
50000 at 260 nm in methanol
application(s)
diagnostic assay manufacturing
hematology
histology
storage temp.
room temp
SMILES string
Cl[H].Nc1ccc2cc3ccc(N)cc3nc2c1
InChI
1S/C13H11N3.ClH/c14-10-3-1-8-5-9-2-4-11(15)7-13(9)16-12(8)6-10;/h1-7H,14-15H2;1H
InChI key
PBBGTVBGXBUVLT-UHFFFAOYSA-N
Application
3, 6-Diaminoacridine hydrochloride has been used for studying cation transfer at the liquid–liquid interface.
An intercalating dye.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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Anirban Basu et al.
Journal of photochemistry and photobiology. B, Biology, 165, 42-50 (2016-10-22)
Interaction of proflavine with hemoglobin (Hgb) was studied employing spectroscopy, calorimetry, and atomic force microscopy. The equilibrium constant was found to be of the order 10
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Journal of biomolecular structure & dynamics, 38(6), 1590-1597 (2019-05-07)
The binding of proflavine, an acriflavine derivative, with the RNA polynucletodide polyadenylic acid-polyuridylic acid is investigated here to understand the structural and thermodynamic basis of the binding process. Such binding data are crucial for designing viable theraperutic agents. Spectroscopic studies
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A DNA sensor has been developed for the determination of doxorubicin by consecutive electropolymerization of an equimolar mixture of Azure B and proflavine and adsorption of native DNA from salmon sperm on a polymer film. Electrochemical investigation showed a difference
Miklós Nagy et al.
Scientific reports, 9(1), 8250-8250 (2019-06-05)
Amino-isocyanoacridines (ICAAcs), as first members of their class, turned out to be a novel, multifunctional acridine orange (AO) type dye family with a number of additional favorable properties. They have enhanced solvatochromic emission range, low quantum yields (ΦF = 2.9-0.4%) in water
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