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Key Documents

13-1100

Sigma-Aldrich

β-Thujaplicin

SAJ special grade, ≥99.0%

Synonym(s):

2-Hydroxy-4-isopropyl-2,4,6-cycloheptatrien-1-one, Hinokitiol

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About This Item

Empirical Formula (Hill Notation):
C10H12O2
CAS Number:
Molecular Weight:
164.20
EC Number:
MDL number:
UNSPSC Code:
12352200
PubChem Substance ID:

grade

SAJ special grade

Assay

≥99.0%

availability

available only in Japan

bp

140 °C/10 mmHg (lit.)

mp

50-52 °C (lit.)

SMILES string

CC(C)C1=CC=CC(=O)C(O)=C1

InChI

1S/C10H12O2/c1-7(2)8-4-3-5-9(11)10(12)6-8/h3-7H,1-2H3,(H,11,12)

InChI key

FUWUEFKEXZQKKA-UHFFFAOYSA-N

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Storage Class Code

13 - Non Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Tsair-Bor Yen et al.
Bioresource technology, 99(11), 4871-4877 (2007-11-06)
The ethanolic extract of Calocedrus macrolepis var. formosana heartwood was screened for antifungal compounds by agar dilution assay and liquid chromatography. Two compounds, beta-thujaplicin and gamma-thujaplicin, responsible for the antifungal property of C. macrolepis var. formosana heartwood were isolated by
Yu-Jing Zhu et al.
Journal of enzyme inhibition and medicinal chemistry, 25(6), 798-803 (2010-06-29)
The inhibitory effects of hinokitiol, a constituent of the woody oils isolated from Cupressaceae heartwood, on mushroom tyrosinase and melanin formation in B16 melanoma cells as well as its antimicrobial activity were investigated. Our results showed that hinokitiol could strongly
S L Hwang et al.
Journal of microencapsulation, 25(5), 351-356 (2008-05-10)
Nanocapsules containing hinokitiol (HKL) were prepared by an emulsion-diffusion method. In an emulsification step in preparing nanocapsules, cetyltrimethylamonium chloride (CTAC) was employed as a cationic emulsifier, Poly(epsilon-caprolactone) (PCL) was use as a wall material and HKL dissolved in octylsalicylate (OS)
Se Eun Byeon et al.
Planta medica, 74(8), 828-833 (2008-06-10)
In this study, we examined the modulatory effect of hinokitiol (HK) on the production of tumor necrosis factor (TNF)-alpha, a critical factor involved in skin inflammation and hair follicle apoptosis. HK effectively suppressed TNF-alpha production in lipopolysaccharide (LPS)-activated, macrophage-like (RAW264.7)
Ransika De Alwis et al.
Journal of plant physiology, 166(7), 720-728 (2008-11-26)
Elicitor treatment initiates defense responses in cultured Cupressus lusitanica cells. In order to investigate the defense mechanism with a yeast extract elicitor, we carried out solid-phase microextraction coupled with gas chromatography for monoterpene analysis. Ten hydrocarbon monoterpenes, including high amounts

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