375115

Heparin Cofactor II, Human Plasma

Heparin Cofactor II, Human Plasma, is a native human plasma protein that ihibits thrombin by forming a bimolecular complex in the presence of heparin. It shares homology with antithrombin III

• Synonym(s): Antithrombin BM
• UNSPSC Code: 12352202
• NACRES: NA.77

Properties

• Quality Level: 100
• Assay: ≥90% (SDS-PAGE)
• form: liquid
• specific activity: ≥700 units/mg protein
• manufacturer/tradename: Calbiochem^®
• storage condition: OK to freeze
• impurities: <2% antigenic ATIII
• shipped in: ambient
• storage temp.: −20°C

Description

General description

Native heparin cofactor II from human plasma. Inhibits thrombin by forming a bimolecular complex in the presence of heparin. Serine proteinase plasma glycoprotein.

Packaging

Please refer to vial label for lot-specific concentration.

Warning

Toxicity: Standard Handling (A)

Unit Definition

One unit is defined as the amount of heparin cofactor II that will inhibit 1 NIH unit of thrombin.

Physical form

In 50% aqueous glycerol.

Preparation Note

Prepared from plasma that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.

Reconstitution

Following initial thaw, aliquot and freeze (-20°C).

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

RESEARCH USE ONLY. This product is regulated in France when intended to be used for scientific purposes, including for import and export activities (Article L 1211-1 paragraph 2 of the Public Health Code). The purchaser (i.e. enduser) is required to obtain an import authorization from the France Ministry of Research referred in the Article L1245-5-1 II. of Public Health Code. By ordering this product, you are confirming that you have obtained the proper import authorization.

Safety Information

• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 1
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable