A44509
α-Amino-γ-butyrolactone hydrobromide
99%
Synonym(s):
(±)-α-Amino-γ-butyrolactone hydrobromide, DL-Homoserine lactone hydrobromide
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About This Item
Empirical Formula (Hill Notation):
C4H7NO2 · HBr
CAS Number:
Molecular Weight:
182.02
Beilstein:
4530084
EC Number:
MDL number:
UNSPSC Code:
12352202
PubChem Substance ID:
NACRES:
NA.22
Pricing and availability is not currently available.
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Assay
99%
form
crystalline
color
white to light yellow
mp
220-225 °C (lit.)
application(s)
peptide synthesis
SMILES string
Br[H].NC1CCOC1=O
InChI
1S/C4H7NO2.BrH/c5-3-1-2-7-4(3)6;/h3H,1-2,5H2;1H
InChI key
MKLNTBLOABOJFZ-UHFFFAOYSA-N
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Signal Word
Warning
Hazard Statements
Precautionary Statements
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
Target Organs
Respiratory system
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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Steven E A Christiaen et al.
Journal of microbiological methods, 87(2), 213-219 (2011-08-23)
A large number of Gram-negative pathogens produce N-acylhomoserine lactones (AHLs) as signal molecules for quorum sensing (QS). This cell-cell communication system allows them to coordinate gene expression and regulate virulence. Therefore, strategies to inhibit QS are promising for the control
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Molecular plant pathology, 14(3), 279-292 (2012-11-14)
Virulence factor regulator (Vfr) is a member of the cyclic 3',5'-adenosine monophosphate (cAMP) receptor proteins that regulate the expression of many important virulence genes in Pseudomonas aeruginosa. The role of Vfr in pathogenicity has not been elucidated fully in phytopathogenic
Cao Xu et al.
Wei sheng wu xue bao = Acta microbiologica Sinica, 51(6), 769-775 (2011-08-27)
Quorum-sensing (QS) is a regulatory mechanism with which bacteria regulate the gene expression according to their population density. Pseudomonas aeruginosa regulates the expression of multiple genes via a hierarchical quorum-sensing cascade through LasR and RhlR and their cognate signal molecules
Xiaopeng Guo et al.
Wei sheng wu xue bao = Acta microbiologica Sinica, 51(9), 1200-1204 (2011-12-01)
Methanosaeta harundinacea 6Ac displayed a cell-density dependent cell morphology transition between short rods (3 microm - 5 microm) and filaments ( >200 microm), implying a quorum sensing system in this archaeon. This study aimed to confirm that cell morphology related
Ariel A Romano et al.
Journal of inorganic biochemistry, 107(1), 96-103 (2011-12-20)
Bacteria use small diffusible molecules to exchange information in a process called quorum sensing (QS). An important class of quorum sensing molecules used by Gram-negative bacteria is the family of N-acylhomoserine lactones (HSL). It was recently discovered that a degradation
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