Skip to Content
Merck
All Photos(2)

Documents

911461

Sigma-Aldrich

Polyester bis-MPA dendron, 2 NHBoc, 1 NHS (core)

generation 1

Synonym(s):

Bis-MPA dendron, NHS-NHBoc dendron

Sign Into View Organizational & Contract Pricing
All Photos(2)

About This Item

Empirical Formula (Hill Notation):
C25H39N3O12
Molecular Weight:
573.59
UNSPSC Code:
12162002
NACRES:
NA.23

description

NHBoc, 1 NHS (core)

form

solid or liquid

mol wt

generation 1

no. Surface Groups

2

color

colorless to white

functional group

(NHS(core))

storage temp.

−20°C

Related Categories

General description

  • Polymer architecture: Dendron
  • End Group Functionality: NHBoc
  • Bis-MPA : 2,2-bis(hydroxymethyl)propionic acid

Application

Bis-MPA dendritic molecules are based on 2,2-bismethylolpropionicacid (bis-MPA) building blocks. The hydrolysable linkers presented in this type of polymers allows their degradation into byproducts that can be reabsorbed by the body or into excretable non-toxic small molecules. Therefore, this group of dendritic polymers are biocompatible and biodegradable, making them suitable for biomedical applications. The NHBoc-functionalized corona and NHS-functionalized core of this product can be readily used in bioconjugation reactions.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Chemistry of multifunctional polymers based on bis-MPA and their cutting-edge applications.
Garcia-Gallego S, et al
Progress in Polymer Science, 48, 85-110 (2015)
Anna Carlmark et al.
Chemical Society reviews, 42(13), 5858-5879 (2013-05-01)
Dendritic polymers are highly branched, globular architectures with multiple representations of functional groups. These nanoscale organic frameworks continue to fascinate researchers worldwide and are today under intensive investigation in application-driven research. A large number of potential application areas have been

Articles

Dendritic Polyester Scaffolds for Drug Delivery

Dendritic molecules' biomedical applications, particularly bis-MPA dendritic scaffolds, hold promise for drug delivery.

Dendritic Polyester Scaffolds for Drug Delivery

Dendritic molecules' biomedical applications, particularly bis-MPA dendritic scaffolds, hold promise for drug delivery.

Dendritic Polyester Scaffolds for Drug Delivery

Dendritic molecules' biomedical applications, particularly bis-MPA dendritic scaffolds, hold promise for drug delivery.

Dendritic Polyester Scaffolds for Drug Delivery

Dendritic molecules' biomedical applications, particularly bis-MPA dendritic scaffolds, hold promise for drug delivery.

See All

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service