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Sigma-Aldrich

N-Phenylanthranilic acid

technical, ≥95% (T)

Synonym(s):

2-(Phenylamino)benzoic acid, Diphenylamine-2-carboxylic acid, DpC

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About This Item

Linear Formula:
2-(C6H5NH)C6H4CO2H
CAS Number:
91-40-7
Molecular Weight:
213.23
Beilstein:
1456607
EC Number:
202-066-8
MDL number:
MFCD00002421
UNSPSC Code:
12352200
PubChem Substance ID:
57652726

grade

technical

Assay

≥95% (T)

form

powder

mp

182-185 °C (lit.)
182-185 °C

application(s)

peptide synthesis

SMILES string

OC(=O)c1ccccc1Nc2ccccc2

InChI

1S/C13H11NO2/c15-13(16)11-8-4-5-9-12(11)14-10-6-2-1-3-7-10/h1-9,14H,(H,15,16)

InChI key

ZWJINEZUASEZBH-UHFFFAOYSA-N

Gene Information

human ... TTR(7276)

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Storage Class Code

13 - Non Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Walter E Finkbeiner et al.
American journal of physiology. Lung cellular and molecular physiology, 301(4), L402-L414 (2011-07-05)
We investigated how cystic fibrosis (CF) alters the relationship between Cl(-) and mucin secretion in cultures of non-CF and CF human tracheobronchial gland mucous (HTGM and CFTGM, respectively) cells. Biochemical studies showed that HTMG cells secreted typical airway mucins, and
Graham R Betton et al.
Toxicologic pathology, 40(4), 682-694 (2012-02-04)
N-phenylanthranilic acid is a chloride channel blocker that causes renal papillary necrosis in rats. Studies were conducted in two strains of male rats to evaluate novel biomarkers of nephrotoxicity. Han-Wistar rats were given daily oral doses of 50, 350, or
Tarek Aboul-Fadl et al.
Molecules (Basel, Switzerland), 16(5), 3544-3551 (2011-04-30)
A facile and efficient method for synthesis of fenamic acid hydrazides from their acids in one-step reaction under microwave irradiation and solvent-free conditions was developed. Compared with the two-step conventional heating method, the process was simple, the reaction time was
Ernie Harpur et al.
Toxicological sciences : an official journal of the Society of Toxicology, 122(2), 235-252 (2011-05-20)
This study reports the evaluation of four urinary biomarkers of renal toxicity, α-glutathione-S-transferase (α-GST), μ-GST, clusterin, and renal papillary antigen-1 (RPA-1), in male Sprague-Dawley and Han-Wistar rats given cisplatin, gentamicin, or N-phenylanthranilic acid (NPAA). Kidney injury was diagnosed histopathologically, according
Asher Peretz et al.
Proceedings of the National Academy of Sciences of the United States of America, 107(35), 15637-15642 (2010-08-18)
The pore and gate regions of voltage-gated cation channels have been often targeted with drugs acting as channel modulators. In contrast, the voltage-sensing domain (VSD) was practically not exploited for therapeutic purposes, although it is the target of various toxins.
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