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750026

Sigma-Aldrich

3α,5β-Tetrahydroaldosterone

≥98% (CP)

Synonym(s):

11β,18-Epoxy-3α,18,21-trihydroxy-5β-pregnan-20-one, 5β-Pregnan-11β,18-epoxy-3α,18,21-triol-20-one

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About This Item

Empirical Formula (Hill Notation):
C21H32O5
CAS Number:
13489-75-3
Molecular Weight:
364.48
MDL number:
MFCD00063459
UNSPSC Code:
12352211
PubChem Substance ID:
329766040
NACRES:
NA.24
Pricing and availability is not currently available.

Quality Level

200

Assay

≥98% (CP)

form

powder

technique(s)

mass spectrometry (MS): suitable

storage temp.

−20°C

SMILES string

C[C@]12CC[C@@H](O)C[C@H]1CC[C@H]3[C@@H]4CC[C@H](C(=O)CO)[C@@]45C[C@H](O[C@@H]5O)[C@H]23

InChI

1S/C21H32O5/c1-20-7-6-12(23)8-11(20)2-3-13-14-4-5-15(16(24)10-22)21(14)9-17(18(13)20)26-19(21)25/h11-15,17-19,22-23,25H,2-10H2,1H3/t11-,12-,13+,14+,15-,17+,18-,19+,20+,21-/m1/s1

InChI key

JDEYOKPHRJVBQO-BMDKAXIVSA-N

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Packaging

This product may be available from bulk stock and can be packaged on demand. For information on pricing, availability and packaging, please contact Stable Isotopes Customer Service.

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H317

Precautionary Statements

P280 - P333 + P313

Hazard Classifications

Skin Sens. 1

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
MBBD7652
MBBD4335
MBBD4718
MBBD2777
MBBD0576

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M Egfjord et al.
Metabolism: clinical and experimental, 42(4), 470-476 (1993-04-01)
The effect of uremia on hepatic metabolism of aldosterone was studied in the isolated perfused liver of female Wistar rats. Uremia was induced by five-sixths partial nephrectomy 4 weeks before experiments. Isolated livers of normal and uremic rats were perfused
T Miyazaki et al.
Endocrinologia japonica, 32(4), 505-509 (1985-08-01)
After a large amount of aldosterone was injected into a male rabbit, urine was collected for 48 h. Separation of urinary aldosterone metabolites into monoglucosiduronate fraction and monosulphate fraction was carried out by a combination of countercurrent distribution and DEAE-Sephadex
T Miyazaki et al.
Endocrinologia japonica, 34(2), 161-169 (1987-04-01)
Analysis of urinary metabolites of [1, 2-3H]-aldosterone was performed in the male guinea-pig. Separation of urinary metabolites was carried out by countercurrent distribution followed by DEAE-Sephadex A-25 column chromatography. A major component was obtained which was both hydrolyzable with sulphatase
M Egfjord et al.
The American journal of physiology, 260(4 Pt 2), F536-F548 (1991-04-01)
The metabolism of aldosterone (Aldo) at 4 nM was studied by radioimmunoassay and by high-performance liquid chromatography in isolated perfused liver (IPL), isolated perfused kidney (IPK), and combined isolated perfused liver and kidney (CIPLK) of male Wistar rats. Effect of
B J Koopman et al.
Journal of chromatography, 378(2), 283-292 (1986-06-13)
A newly devised procedure for a simultaneous determination of urinary tetrahydroaldosterone and aldosterone is described. The procedure is based on deconjugation and acetalization, followed by extraction and derivatization of the urinary compounds to their trimethylsilyl ethers and subsequent gas chromatographic-mass
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