Journal of immunological methods, 54(3), 355-360 (1982-11-12)
In the past, the lesions of experimental allergic encephalomyelitis (EAE) have been induced to localize around brain tissue damaged by anoxia or direct physical or chemical attack. The procedure for producing the requisite antecedent brain injury has been simplified by
Journal of neuropathology and experimental neurology, 41(2), 233-240 (1982-03-01)
The administration of an aliphatic triamine, 3,3'-methylimino-bis-(N-methylpropylamine), was used to produce non-necrotizing lesions in the hypothalamus and medulla oblongata of rats. The distribution of the lesions in the hypothalamus was similar to that produced by goldthioglucose, and consisted ultrastructurally of
Journal of neuropathology and experimental neurology, 41(1), 45-53 (1982-01-01)
The clinical and pathologic features of two brothers with the adult form of Gaucher's disease, both of whom developed cerebral glioblastoma multiforme, are presented. Neither patient had a long-standing neurologic disorder, and morphologic evidence of nervous system glucocerebroside storage was
An aliphatic triamine has been reported to cause lesions in rats in the vicinity of the area postrema and the median eminence of the hypothalamus, sites known to lack a blood-brain barrier. The present study revealed that some of the
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