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542709

Sigma-Aldrich

2,6-Difluorobenzenesulfonamide

97%

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About This Item

Linear Formula:
F2C6H3SO2NH2
CAS Number:
Molecular Weight:
193.17
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22

Assay

97%

mp

187-191 °C (lit.)

SMILES string

NS(=O)(=O)c1c(F)cccc1F

InChI

1S/C6H5F2NO2S/c7-4-2-1-3-5(8)6(4)12(9,10)11/h1-3H,(H2,9,10,11)

InChI key

RVVVGGCOFWWDEL-UHFFFAOYSA-N

General description

2,6-Difluorobenzenesulfonamide is a fluorinated benzenesulfonamide that can be prepared by reacting 2,6-difluorobenzenesulfonyl chloride with 29% ammonium hydroxide. It forms complexes with human carbonic anhydrase II (HCA). X-ray crystal structure of these complexes have been studied.

Application

2,6-Difluorobenzenesulfonamide can be prepared from N-(4-chlorophenyl)-N′-[(2,6-di fluorophenyl)-sulfonyl]urea.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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