Skip to Content
Merck
All Photos(4)

Documents

461350

Sigma-Aldrich

1-Boc-4-piperidone

98%

Synonym(s):

N-Boc-4-piperidone, tert-Butyl 4-oxo-1-piperidinecarboxylate

Sign Into View Organizational & Contract Pricing
All Photos(4)

About This Item

Empirical Formula (Hill Notation):
C10H17NO3
CAS Number:
79099-07-3
Molecular Weight:
199.25
Beilstein:
3650236
MDL number:
MFCD00151800
UNSPSC Code:
12352100
PubChem Substance ID:
24869846
NACRES:
NA.22

Assay

98%

mp

73-77 °C (lit.)

SMILES string

CC(C)(C)OC(=O)N1CCC(=O)CC1

InChI

1S/C10H17NO3/c1-10(2,3)14-9(13)11-6-4-8(12)5-7-11/h4-7H2,1-3H3

InChI key

ROUYFJUVMYHXFJ-UHFFFAOYSA-N

Looking for similar products? Visit Product Comparison Guide

Related Categories

General description

1-Boc-4-piperidone is used as a precursor in the synthesis of synthetic drugs and as a building block for the preparation of selective ligands.

Application

1-Boc-4-piperidone, a pharma building block, may be used in the synthesis of (3E,5E)-3,5-bis(2,5-dimethoxybenzylidene)-1-t-butoxycarbonylpiperidin-4-one (RL197). It may also be used in the synthesis of spirorifamycins containing a piperidine ring structure.

Warning

Avoid metal contact.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Customers Also Viewed

Slide 1 of 2

1 of 2

Tetrahydro-4H-pyran-4-one 99%

Sigma-Aldrich

198242

Tetrahydro-4H-pyran-4-one

2,3-Diaminopyridine 95%

Sigma-Aldrich

125857

2,3-Diaminopyridine

In Ho Kim et al.
Bioorganic & medicinal chemistry letters, 17(5), 1181-1184 (2006-12-27)
A novel series of spirorifamycins was synthesized and their antibacterial activity evaluated both in vitro and in vivo. This new series of rifamycins shows excellent activity against Staphylococcus aureus that is equivalent to rifabutin. However, some compounds of the series
Gebhard Thoma et al.
Journal of medicinal chemistry, 47(8), 1939-1955 (2004-04-02)
The chemokine receptor CCR5 plays an important role in inflammatory and autoimmune disorders as well as in transplant rejection by affecting the trafficking of effector T cells and monocytes to diseased tissues. Antagonists of CCR5 are believed to be of
John W Clader et al.
Bioorganic & medicinal chemistry, 12(2), 319-326 (2004-01-16)
Anthranilamide analogues such as 23 are potent and highly selective muscarinic M2 antagonists that also show good oral bioavailability and in vivo activity.
Design, synthesis, and structure--activity relationships of novel spiro-piperidines as acetyl-CoA carboxylase inhibitors
Kamata, Makoto and Yamashita
Bioorganic & Medicinal Chemistry Letters, 22, 3643-3647 (2012)
Marlon Cowart et al.
Journal of medicinal chemistry, 47(15), 3853-3864 (2004-07-09)
A new class of agents with potential utility for the treatment of erectile dysfunction has been discovered, guided by the hypothesis that selective D4 agonists are erectogenic but devoid of the side effects typically associated with dopaminergic agents. The lead
View All Related Papers

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service