333131

N,N′-Bis(2-aminoethyl)-1,3-propanediamine

97%

• Synonym(s): 1,3-Bis(2-aminoethylamino)propane, 1,4,8,11-Tetraazaundecane, 1,9-Diamino-3,7-diazanonane, 3,7-Diaza-1,9-diaminononane, 3,7-Diazanonane-1,9-diamine, Ethylene(trimethylene)ethylenetetramine, N,N′-Bis(2-aminoethyl)propane-1,3-diamine, N1,N3-Bis(2-aminoethyl)-1,3-propanediamine, Triethylene 2,3,2 tetramine
• Linear Formula: H₂NCH₂CH₂NH(CH₂)₃NHCH₂CH₂NH₂
• CAS Number: 4741-99-5
• Molecular Weight: 160.26
• Beilstein: 1742732
• EC Number: 225-254-1
• MDL number: MFCD00008174
• UNSPSC Code: 12352100
• PubChem Substance ID: 24860105
• NACRES: NA.22

Properties

• Assay: 97%
• form: liquid
• refractive index: n20/D 1.494 (lit.)
• bp: 142-145 °C/8 mmHg (lit.)
• density: 0.96 g/mL at 25 °C (lit.)
• functional group: amine
• SMILES string: NCCNCCCNCCN
• InChI: 1S/C7H20N4/c8-2-6-10-4-1-5-11-7-3-9/h10-11H,1-9H2
• InChI key: UWMHHZFHBCYGCV-UHFFFAOYSA-N

Description

General description

N,N′-Bis(2-aminoethyl)-1,3-propanediamine is a high affinity Cu(II) chelator.[1] It inhibits mitochondrial cytochrome c oxidase by causing cellular Cu deficiency in a human promyelocytic leukemia cell line (HL-60).[2]

Application

N,N′-Bis(2-aminoethyl)-1,3-propanediamine was used to study the regulation of gene that encodes the periplasmic superoxide dismutase of Escherichia coli in response to copper.[1]

Safety Information

• Pictograms: GHS05
• Signal Word: Danger
• Hazard Statements: H314
• Precautionary Statements: P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338 - P363 - P405
• Hazard Classifications: Skin Corr. 1B
• Storage Class Code: 8A - Combustible corrosive hazardous materials
• WGK: WGK 3
• Flash Point(F): 230.0 °F - closed cup
• Flash Point(C): 110 °C - closed cup
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves