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Supelco

1,1,2-Trichlorotrifluoroethane

HPLC grade, ≥99.9%

Synonym(s):

1,1,2-Trichloro-1,2,2-trifluoroethane, 1,1,2-Trichloro-trifluoroethane, Genetron® 113

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About This Item

Linear Formula:
ClCF2CCl2F
CAS Number:
76-13-1
Molecular Weight:
187.38
Beilstein:
1740335
EC Number:
200-936-1
MDL number:
MFCD00000782
UNSPSC Code:
12190000
PubChem Substance ID:
329752932

grade

HPLC grade

vapor density

6.5 (vs air)

vapor pressure

5.5 psi ( 20 °C)

Assay

≥99.9%

form

liquid

autoignition temp.

1256 °F

technique(s)

HPLC: suitable

impurities

<0.010% water

evapn. residue

<0.0005%

refractive index

n20/D 1.358 (lit.)

bp

47-48 °C (lit.)

mp

−35 °C (lit.)

density

1.57 g/mL at 25 °C (lit.)

λ

H2O reference

UV absorption

λ: 231 nm Amax: 1.00
λ: 240 nm Amax: 0.20
λ: 260-400 nm Amax: 0.01

SMILES string

FC(F)(Cl)C(F)(Cl)Cl

InChI

1S/C2Cl3F3/c3-1(4,6)2(5,7)8

InChI key

AJDIZQLSFPQPEY-UHFFFAOYSA-N

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Packaging

Packaged under nitrogen, bottles are Sealed for Quality™

Legal Information

Genetron is a registered trademark of Honeywell International Inc.

Pictograms

Exclamation markEnvironment
GHS07,GHS09

Signal Word

Warning

Hazard Statements

H319,H411,H420

Hazard Classifications

Aquatic Chronic 2 - Eye Irrit. 2 - Ozone 1

Storage Class Code

10 - Combustible liquids

WGK

WGK 2

Flash Point(F)

383.0 °F

Flash Point(C)

195 °C

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Yun-Ru Chen et al.
Oncotarget, 7(2), 1984-1999 (2015-12-18)
Macroautophagy can promote cellular survival or death depending on the cellular context and its extent. We hypothesized that autophagy induction would synergize with a therapeutic agent targeting the autophagic cargo. To test this hypothesis, we treated breast cancer MDA-MB-231 cells
Wei Chen et al.
Autophagy, 10(7), 1272-1284 (2014-06-07)
Ribonucleotide reductase (RNR) plays a critical role in catalyzing the biosynthesis and maintaining the intracellular concentration of 4 deoxyribonucleoside triphosphates (dNTPs). Unbalanced or deficient dNTP pools cause serious genotoxic consequences. Autophagy is the process by which cytoplasmic constituents are degraded
M Neghab et al.
International archives of occupational and environmental health, 70(3), 187-194 (1997-01-01)
The objectives of this study were threefold. First, to examine the hepatic effects of occupational exposure to 1,1,2-trichloro-1,2,2-trifluoroethane (FC 113) using conventional and newer tests (serum bile acids) of hepatobiliary function. Second, to assess the effects of altered work practices
T Kawakami et al.
Toxicology and industrial health, 6(3-4), 493-498 (1990-05-01)
The interaction of Freon 113 (1,1,2-trichloro-1,2,2-trifluoroethane) and hypoxia on the heart conduction system was studied using electrocardiogram monitoring of isolated perfused rat hearts. Freon 113 (0.2 mM) alone elicited significant atrioventricular conduction delay (p less than 0.05) and heart rate
J D Kaufman et al.
American journal of industrial medicine, 25(5), 731-735 (1994-05-01)
Two cases of atrial fibrillation and one case of sudden death occurred in workers exposed to trifluorotrichloroethane (CFC 113) as a solvent/degreasing agent. This agent and related halogenated hydrocarbons are widely used in industry as solvents and degreasing agents, and
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