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268895

Sigma-Aldrich

1-Methoxy-2-propanol

98%

Synonym(s):

Propylene glycol methyl ether, Propyleneglycol monomethyl ether

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About This Item

Linear Formula:
CH3CH(OH)CH2OCH3
CAS Number:
Molecular Weight:
90.12
Beilstein:
1731270
EC Number:
MDL number:
UNSPSC Code:
12352103
PubChem Substance ID:

vapor density

3.12 (vs air)

vapor pressure

10.9 mmHg ( 25 °C)

Assay

98%

autoignition temp.

532 °F

expl. lim.

13.8 %

refractive index

n20/D 1.403 (lit.)

bp

118-119 °C (lit.)
118-119 °C

density

0.916 g/mL at 25 °C (lit.)

SMILES string

CC(O)COC

InChI

1S/C4H10O2/c1-4(5)3-6-2/h4-5H,3H2,1-2H3

InChI key

ARXJGSRGQADJSQ-UHFFFAOYSA-N

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Pictograms

FlameExclamation mark

Signal Word

Warning

Hazard Statements

Hazard Classifications

Flam. Liq. 3 - STOT SE 3

Target Organs

Central nervous system

Storage Class Code

3 - Flammable liquids

WGK

WGK 1

Flash Point(F)

93.2 °F - closed cup

Flash Point(C)

34 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Juergen Brieger et al.
Toxicology letters, 177(2), 138-143 (2008-02-26)
To evaluate the impact of 1-methoxypropanol-2 (MEP) for the stimulation of an inflammatory response in human respiratory mucosa, we exposed 22 primary cell cultures of nasal respiratory epithelia of healthy individuals to MEP concentrations at the level of the German
S R Vink et al.
Regulatory toxicology and pharmacology : RTP, 58(1), 64-71 (2010-04-17)
REACH requests the exploration of alternative strategies for hazard identification before resorting to (in vivo) testing. Here, we combined read-across as non-testing strategy with a tiered exposure assessment for the risk characterisation of 1-methoxypropan-2-ol (PGME) as a representative for phase-in
A Muttray et al.
Toxicology letters, 220(2), 187-192 (2013-04-30)
The German MAK value of 1-methoxypropanol-2 has been fixed at 100 ppm. The aim of this study was to evaluate possible acute effects of an exposure to 100 ppm 1-methoxypropanol-2 on the upper airways of human subjects. Twenty subjects were
Catherine Tomicic et al.
Analytical and bioanalytical chemistry, 396(7), 2709-2714 (2010-02-16)
Glycol ethers still continue to be a workplace hazard due to their important use on an industrial scale. Currently, chronic occupational exposures to low levels of xenobiotics become increasingly relevant. Thus, sensitive analytical methods for detecting biomarkers of exposure are
W R Berendsen et al.
Biotechnology and bioengineering, 95(5), 883-892 (2006-08-29)
Lipase-catalyzed kinetic resolution of racemates is a popular method for synthesis of chiral synthons. Most of these resolutions are reversible equilibrium limited reactions. For the first time, an extensive kinetic model is proposed for kinetic resolution reactions, which takes into

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