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Merck

FCAR

Fc fragment of IgA, receptor for

Synonyms:
CD89
Species:
UniProtKB ID:
Gene ID:
  • Human(2204) Summary: This gene is a member of the immunoglobulin gene superfamily and encodes a receptor for the Fc region of IgA. The receptor is a transmembrane glycoprotein present on the surface of myeloid lineage cells such as neutrophils, monocytes, macrophages, and eosinophils, where it mediates immunologic responses to pathogens. It interacts with IgA-opsonized targets and triggers several immunologic defense processes, including phagocytosis, antibody-dependent cell-mediated cytotoxicity, and stimulation of the release of inflammatory mediators. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008]
  • Rat(365183) Fc fragment of IgA, receptor for
  • Horse(100050205) Fc fragment of IgA, receptor for
  • cow(503555) Fc fragment of IgA, receptor for
  • domestic guinea pig(100716057) Fc fragment of IgA, receptor for

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ELISA

Product Number
Description
Species
Human FCAR ELISA, for serum, plasma and cell culture supernatants,
Species
human

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-FCAR antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
western blot
Monoclonal Anti-CD89 antibody produced in mouse, clone A59,
Species Reactivity
human, nonhuman primates
Application
flow cytometry

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human FCAR,
Species
human