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Merck

TRUEPVAF

TrueGel3D Polymer

modified for fast gelling (FAST-PVA)

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About This Item

NACRES:
NA.71
UNSPSC Code:
12352207
Biological source:
synthetic
Technique(s):
cell attachment: suitable
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biological source

synthetic

technique(s)

cell attachment: suitable

shipped in

dry ice

storage temp.

−70°C

General description

PVA polymers are functionalized with thiol-reactive maleimide groups, which react rapidly with thiol groups of crosslinkers to form hydrogels in few seconds. The thiol-reactive maleimide groups are also compatible to conjugate polymers with bioactive factors. The thioglycerol is used to maintain hydrogel strength and also as a control to compare cellular behavior in peptide-modified versus unmodified hydrogels. The buffers (pH7.2 and pH 5.5) are used to control pH and osmotic conditions to optimize time for gelation.

Application

FAST-PVA polymer is used with crosslinkers (CD/PEG crosslinkers) to establish stable hydrogels.

Features and Benefits

  • Contains synthetic polymer (PVA) functionalized with maleimide groups for quick gelation
  • Non degradable polymer

Other Notes

TRUEPVAF contains FAST-PVA solution in phosphate buffer, TrueGel3D thioglycerol and water.

Disclaimer

Avoid frequent freeze-thaw cycles and store FAST-PVA polymer in small portions.


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pictograms

Corrosion

signalword

Warning

hcodes

Hazard Classifications

Met. Corr. 1

flash_point_f

Not applicable

flash_point_c

Not applicable

Storage Class

10 - Combustible liquids



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