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Merck

SML3598

1PBC

≥98% (HPLC)

Synonym(s):

1-Hydroxy-3-(trifluoromethyl)pyrido[1,2-a]benzimidazole-4-carbonitrile

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About This Item

Empirical Formula (Hill Notation):
C13H6F3N3O
CAS Number:
Molecular Weight:
277.20
UNSPSC Code:
12352200
NACRES:
NA.21
MDL number:
Assay:
≥98% (HPLC)
Form:
powder
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Quality Segment

assay

≥98% (HPLC)

form

powder

color

white to beige

solubility

DMSO: 2 mg/mL, clear (Warmed)

storage temp.

-10 to -25°C

SMILES string

OC1=CC(C(F)(F)F)=C(C#N)C2=NC3=CC=CC=C3N21

Biochem/physiol Actions

1PBC is a potent and selective blocker of TMEM16A calcium-activated chloride channel that interacts with the anion pore. Also, 1PBC is a potent inhibitor of TMEM16F channel.
Potent and selective blocker of TMEM16A calcium-activated chloride channel; potent inhibitor of TMEM16F channel


Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable



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