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SML3548

8RK64

≥98% (HPLC)

Synonym(s):

(S)-N-(5-(2-azidoacetyl)-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridin-2-yl)-1-cyanopyrrolidine-3-carboxamide

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About This Item

Empirical Formula (Hill Notation):
C14H16N8O2S
CAS Number:
2705841-52-5
Molecular Weight:
360.39
UNSPSC Code:
41121800
NACRES:
NA.21
Assay:
≥98% (HPLC)
Form:
powder
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Quality Segment

100

assay

≥98% (HPLC)

form

powder

color

white to beige

solubility

DMSO: 2 mg/mL, clear

storage temp.

2-8°C

SMILES string

O=C([C@H]1CCN(C#N)C1)NC2=NC3=C(S2)CN(C(CN=[N+]=[N-])=O)CC3

InChI key

KIWKRCCIHSGWQS-VIFPVBQESA-N

Biochem/physiol Actions

8RK64 is a cell penetrant, potent and selective covalent inhibitor of UCHL1 (ubiquitin carboxy-terminal hydrolase L1) that binds to the active-site cysteine residue of UCHL1. 8RK64 potently inhibits UCHL1 activity in cells.
Cell penetrant, potent and selective covalent inhibitor of UCHL1

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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