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Merck

SML2835

SGC-CAMKK2-1N

≥98% (HPLC)

Synonym(s):

2-Chloro-4-(5-phenylfuro[2,3-b]pyridin-3-yl)benzoic acid, SGC-CAMKK2-1 inactive control, SGC-CAMKK2-1 negative control, YL-36 inactive control, YL-36 negative control

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About This Item

Empirical Formula (Hill Notation):
C20H12ClNO3
Molecular Weight:
349.77
NACRES:
NA.77
UNSPSC Code:
12352200
Assay:
≥98% (HPLC)
Form:
powder
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Quality Segment

assay

≥98% (HPLC)

form

powder

color

white to beige

solubility

DMSO: 2 mg/mL, clear

storage temp.

2-8°C

Biochem/physiol Actions

Inactive analog of and negative control for the potent and selective CaM kinase kinase (CaMKK) inhibitor SGC-CAMKK2-1 (YL-36).
SGC-CAMKK2-1N is an inactive analog of and negative control for the potent and selective CaM kinase kinase (CaMKK) inhibitor SGC-CAMKK2-1 (YL-36). SGC-CAMKK2-1N inhibits CaMKK2 with an IC50 of 27 μM in cell-free assays (IC50 = 30 nM by SGC-CAMKK2-1) and shows no cellular potency.


Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable



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