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Merck

SML2466

OXFBD04

≥98% (HPLC)

Synonym(s):

3-(3,5-dimethylisoxazol-4-yl)-5-(hydroxy(pyridin-3-yl)methyl)phenol

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About This Item

Empirical Formula (Hill Notation):
C17H16N2O3
CAS Number:
Molecular Weight:
296.32
UNSPSC Code:
12352200
NACRES:
NA.77
Assay:
≥98% (HPLC)
Form:
powder
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assay

≥98% (HPLC)

form

powder

color

white to beige

solubility

DMSO: 2 mg/mL, clear

storage temp.

2-8°C

SMILES string

CC1=NOC(C)=C1C2=CC(C(O)C3=CN=CC=C3)=CC(O)=C2

InChI key

RFDVEAHRRMEOHK-UHFFFAOYSA-N

Biochem/physiol Actions

BRD4 inhibitor
OXFBD04 is a potent and selective inhibitor of BRD4(1) that inhibits interactions of BRD4with the RelA subunit of NF-κB. OXFBD02 inhibits proliferation of various cancer cell lines including leukaemia, breast, and renal cancer cell lines.


Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable



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