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Carprofen

Name: Carprofen
Brand: SIGMA

≥97% (HPLC), COX-2 inhibitor, powder

Synonym(s):

6-Chloro-α-methyl-9H-carbazole-2-acetic acid

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About This Item

Empirical Formula (Hill Notation):

C₁₅H₁₂ClNO₂

CAS Number:

53716-49-7

Molecular Weight:

273.71

NACRES:

NA.77

PubChem Substance ID:

329826035

UNSPSC Code:

12352200

EC Number:

258-712-4

MDL number:

MFCD00079028

Assay:

≥97% (HPLC)

Form:

powder

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Properties

Product Name

Carprofen, ≥97% (HPLC)

Quality Segment

100

assay

≥97% (HPLC)

form

powder

color

white to beige

solubility

DMSO: 20 mg/mL, clear

storage temp.

room temp

SMILES string

CC(C(O)=O)c1ccc2c(c1)[nH]c3ccc(Cl)cc23

InChI

1S/C15H12ClNO2/c1-8(15(18)19)9-2-4-11-12-7-10(16)3-5-13(12)17-14(11)6-9/h2-8,17H,1H3,(H,18,19)

InChI key

PUXBGTOOZJQSKH-UHFFFAOYSA-N

Gene Information

human ... PTGS2(5743)

Description

Biochem/physiol Actions

Carprofen is a non-steroidal anti-inflammatory drug (NSAID) that has been found to have antimicrobial activity. Carprofen is primarily used as a veterinary analgesic and anti-inflammatory for arthritis and pain. Its anti-inflammatory activity is due to cyclooxygenase inihbition with selectivity for COX-2 inhibition, while its antimicrobial activity is less certain. Carprofen can kill B. subtilis by permeabilizing its membrane. Other studies have shown carprofen can target the Escherichia coli DNA polymerase III β subunit.

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This Item	PHR1452	33975	Y0000846
Sigma-Aldrich SML1713 Carprofen	Supelco PHR1452 Carprofen	Supelco 33975 Carprofen	Y0000846 Carprofen
description ≥97% (HPLC)	description Pharmaceutical Secondary Standard; Certified Reference Material	description VETRANAL^®, analytical standard	description European Pharmacopoeia (EP) Reference Standard
assay ≥97% (HPLC)	assay -	assay -	assay -
form powder	form -	form -	form -
Quality Level 100	Quality Level 300	Quality Level 100	Quality Level -
storage temp. room temp	storage temp. 2-8°C	storage temp. -	storage temp. 2-8°C
solubility DMSO: 20 mg/mL, clear	solubility -	solubility -	solubility -
color white to beige	color -	color -	color -

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pictograms

GHS06

signalword

Danger

hcodes

H301

pcodes

P264 - P270 - P301 + P310 - P405 - P501

Hazard Classifications

Acute Tox. 3 Oral

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

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