SML0087

MEGX

≥95% (HPLC)

• Synonym(s): MGEX, Monoethylglycinexylidide, N-(2,6-dimethylphenyl)-2-(ethylamino)acetamide, Norlidocaine
• Empirical Formula (Hill Notation): C₁₂H₁₈N₂O
• CAS Number: 7728-40-7
• Molecular Weight: 206.28
• NACRES: NA.77
• PubChem Substance ID: 329825147
• UNSPSC Code: 12352200
• MDL number: MFCD00098991
• Assay: ≥95% (HPLC)
• Form: powder
• Storage condition: desiccated

Properties

• Quality Segment: 100
• assay: ≥95% (HPLC)
• form: powder
• storage condition: desiccated
• color: white to beige
• solubility: H₂O: 10 mg/mL, clear
• storage temp.: 2-8°C
• SMILES string: CC1=C(NC(CNCC)=O)C(C)=CC=C1
• InChI: 1S/C12H18N2O/c1-4-13-8-11(15)14-12-9(2)6-5-7-10(12)3/h5-7,13H,4,8H2,1-3H3,(H,14,15)
• InChI key: WRMRXPASUROZGT-UHFFFAOYSA-N

Description

Application

MEGX has been used in an approach to improve the yield of N-dealkylated lidocaine.

Biochem/physiol Actions

Lidocaine metabolite

Monoethylglycinexylidide (MEGX) is an active metabolite of lidocaine.

MEGX is generated by hepatic cytochrome P-450 system upon oxidative de-ethylation. Measurement of MEGX by immunoassay contributes to liver function test. MEGX possesses antiarrhythmic action and therefore extends lidocaine effect.

Safety Information

• pictograms: GHS06
• signalword: Danger
• hcodes: H301
• pcodes: P264 - P270 - P301 + P310 - P405 - P501
• Hazard Classifications: Acute Tox. 3 Oral
• Storage Class: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• wgk: WGK 1
• flash_point_f: Not applicable
• flash_point_c: Not applicable