SML0011

VAHA

≥98% (HPLC)

• Synonym(s): VAHA, Valproyl hydroxamic acid, VPA-HA
• Empirical Formula (Hill Notation): C₈H₁₇NO₂
• CAS Number: 106132-78-9
• Molecular Weight: 159.23
• NACRES: NA.77
• PubChem Substance ID: 329825087
• UNSPSC Code: 12352200
• MDL number: MFCD12756348
• Assay: ≥98% (HPLC)
• Form: powder

Properties

• Quality Segment: 100
• assay: ≥98% (HPLC)
• form: powder
• solubility: DMSO: ≥25 mg/mL
• storage temp.: 2-8°C
• SMILES string: CCCC(CCC)C(=O)NO
• InChI: 1S/C8H17NO2/c1-3-5-7(6-4-2)8(10)9-11/h7,11H,3-6H2,1-2H3,(H,9,10)
• InChI key: ROJGIRXXBBBMPL-UHFFFAOYSA-N

Description

Application

VAHA may be used in cell signaling studies.

Biochem/physiol Actions

VAHA (Valproyl hydroxamic acid) is an HDAC inhibitor with less activity than valproic acid against Class I enzymes but much greater Class II activity

VAHA is an HDAC inhibitor

Hydroxamic acid derivatives of valproic acid exhibit anticonvulsant activity with no teratogenic activity in mouse neural tube defect model. It is effective in the treatment of bipolar disorders.

Features and Benefits

This compound is a featured product for Gene Regulation research. Click here to discover more featured Gene Regulation products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

Safety Information

• Pictograms: GHS07
• Signal Word: Warning
• Hazard Codes: H302
• Precautionary Statements: P264 - P270 - P301 + P312 - P501
• Hazard Classifications: Acute Tox. 4 Oral
• Storage Class: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable