SAE0153

Leupeptin Ready Made Solution

Non-freezing solution, 5 mg/ml

• NACRES: NA.54
• UNSPSC Code: 12352202
• Assay: ≥90% (HPLC)
• Form: ready-to-use solution

Properties

• biological source: microbial
• Quality Segment: 100
• assay: ≥90% (HPLC)
• form: ready-to-use solution
• concentration: 5 mg/mL
• storage temp.: −20°C

Description

General description

Leupeptin is a tripeptide protease inhibitor that is naturally produced in Actinomyces / Streptomyces. Known also as N-acetyl-L-leucyl-L-leucyl-L-arginal, leupeptin is a reversible competitive inhibitor of cysteine, serine, and thiol proteases.

Features and Benefits

• Inhibitor of serine and cysteine proteases
• Inhibits plasmin, trypsin, papain, calpain, and cathepsin B
• Does not inhibit pepsin, cathepsin A, cathepsin D, thrombin, or α-chymotrypsin
• Effective concentration: 10 μM - 100 μM
• Convenient 5 mM non-freezing solution, ready to dilute to the desired working concentration

Safety Information

• Storage Class: 10 - Combustible liquids
• wgk: WGK 2