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About This Item
Empirical Formula (Hill Notation):
C13H15N3 · C4H4O4
CAS Number:
Molecular Weight:
329.35
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
EC Number:
227-314-2
MDL number:
Quality level:
Product Name
Quipazine maleate salt,
Quality Level
solubility
H2O: soluble, alcohol: soluble, dilute aqueous acid: soluble
storage temp.
2-8°C
SMILES string
OC(=O)\C=C/C(O)=O.C1CN(CCN1)c2ccc3ccccc3n2
InChI
1S/C13H15N3.C4H4O4/c1-2-4-12-11(3-1)5-6-13(15-12)16-9-7-14-8-10-16;5-3(6)1-2-4(7)8/h1-6,14H,7-10H2;1-2H,(H,5,6)(H,7,8)/b;2-1-
InChI key
QYJJDHZHSCTBII-BTJKTKAUSA-N
Gene Information
Application
Quipazine maleate salt has been used as a serotonin receptor agonist to study its effects on mouse models with spinal cord injury. It has also been used as a serotonin receptor agonist to study its effects on the locomotion of zebrafish.
Biochem/physiol Actions
Quipazine belongs to the class of psychedelics and acts as a serotonin/5-hydroxytryptamine-2A/C receptor agonist. It also acts as an inhibitor of prolactin.
signalword
Danger
hcodes
pcodes
Hazard Classifications
Acute Tox. 3 Oral
Storage Class
6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
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Elena Morelli et al.
Journal of medicinal chemistry, 52(11), 3548-3562 (2009-05-12)
The synthesis and the biological characterization of novel highly selective pyrroloquinoxaline 5-HT(3) receptor (5-HT(3)R) ligands are described. In functional and in vivo biological studies the novel quinoxalines modulated cardiac parameters by direct interaction with myocardial 5-HT(3)Rs. The potent 5-HT(3)R ligands
J M Zgombick et al.
Naunyn-Schmiedeberg's archives of pharmacology, 354(3), 226-236 (1996-08-01)
Recombinant human 5-HT1D alpha and 5-HT1D beta receptor subtypes were stably expressed in NIH-3T3 fibroblasts (1D alpha cell line) and Y-1 adrenocortical tumor cells (1D beta cell line), respectively, for pharmacological evaluations of serotonergic compounds to inhibit forskolin-stimulated cAMP accumulation
Sabine Rehm et al.
Birth defects research. Part B, Developmental and reproductive toxicology, 80(3), 253-257 (2007-06-16)
Observations associated with drug-induced hyper- or hypoprolactinemia in rat toxicology studies may be similar and include increased ovarian weight due to increased presence of corpora lutea. Hyperprolactinemia may be distinguished if mammary gland hyperplasia with secretion and/or vaginal mucification is
Global Trade Item Number
| SKU | GTIN |
|---|---|
| Q1004-50MG | 04061832084374 |
| Q1004-250MG | 04061836687694 |
