P9158

Pyridoxamine dihydrochloride

BioReagent, suitable for cell culture

• Synonym(s): 4-(Aminomethyl)-5-hydroxy-6-methyl-3-pyridinemethanol dihydrochloride
• Empirical Formula (Hill Notation): C₈H₁₂N₂O₂ · 2HCl
• CAS Number: 524-36-7
• Molecular Weight: 241.11
• UNSPSC Code: 12352205
• NACRES: NA.75
• PubChem Substance ID: 24899015
• EC Number: 208-357-6
• Beilstein/REAXYS Number: 3632748
• MDL number: MFCD00012808

Properties

• biological source: synthetic (organic)
• Quality Segment: 200
• product line: BioReagent
• assay: ≥98%
• form: powder
• mol wt: M_w 241.11 g/mol
• technique(s): cell culture | mammalian: suitable
• color: white to off-white
• mp: 224-226 °C (dec.) (lit.)
• solubility: water: soluble 50 mg/mL, clear, colorless to faintly yellow
• storage temp.: −20°C
• SMILES string: Cl[H].Cl[H].Cc1ncc(CO)c(CN)c1O
• InChI: 1S/C8H12N2O2.2ClH/c1-5-8(12)7(2-9)6(4-11)3-10-5;;/h3,11-12H,2,4,9H2,1H3;2*1H
• InChI key: HNWCOANXZNKMLR-UHFFFAOYSA-N

Description

Application

Use in mammalian cell culture as an alternative to pyridoxine or pyridoxal. Vitamin B6 is a required component of cell culture media. Historically, media have been supplemented with vitamin B6 in the aldehyde form, pyridoxal. While this is a biologically active form of vitamin B6, it is unstable in liquid media. When cells are able to utilize either pyridoxine and/or pyridoxamine, they are preferred supplement versus pyridoxal. A number of classical media are now offered with a choice between pyridoxal and pyridoxine as the vitamin A source.

Safety Information

• Storage Class: 11 - Combustible Solids
• WGK: WGK 2
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• PPE (personal protective equipment): dust mask type N95 (US), Eyeshields, Gloves