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L-Proline

Name: <SC>L</SC>-Proline
Brand: SIGMA

Synonym(s):

(S)-Pyrrolidine-2-carboxylic acid

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About This Item

Empirical Formula (Hill Notation):

C₅H₉NO₂

CAS Number:

147-85-3

Molecular Weight:

115.13

EC Number:

205-702-2

UNSPSC Code:

12352209

NACRES:

NA.26

Beilstein/REAXYS Number:

80810

MDL number:

MFCD00064318

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Properties

biological source

non-animal source

Quality Segment

400

assay

≥98.5%

form

crystalline powder

technique(s)

cell culture | mammalian: suitable

impurities

endotoxin, heavy metals, residual solvents, tested

mp

228 °C (dec.) (lit.)

solubility

H₂O: 50 mg/mL

application(s)

pharmaceutical (small molecule)

foreign activity

cytotoxicity, tested

SMILES string

OC(=O)[C@@H]1CCCN1

InChI

1S/C5H9NO2/c7-5(8)4-2-1-3-6-4/h4,6H,1-3H2,(H,7,8)/t4-/m0/s1

InChI key

ONIBWKKTOPOVIA-BYPYZUCNSA-N

Description

General description

Our SAFC^® portfolio of high-quality raw materials for use in biopharmaceutical processing withstands strict quality control procedures plus the documentation and expertise to help our customers meet requirements as defined by the M-Clarity Program.

M-Clarity Program

Our comprehensive portfolio of upstream process chemicals not only provides biopharmaceutical manufacturers with high-quality raw materials for production of classical and novel therapies, but also helps them get to market faster and simplify regulatory challenges. Trust us to deliver supply chain transparency and reliable sourcing around the globe, streamlining your product qualification with best-in-class regulatory support and service.

To request documentation for this product, please contact Customer Support and select ‘Product Documentation′. Please note that access to the documentation for this product requires a confidentiality disclosure agreement.

Application

L-Proline is a non-essential amino acid. Peptides bond to Proline, making it a useful building block for proteins. It can be used as a cell culture media component for the commercial biomanufacture of therapeutic recombinant proteins and monoclonal antibodies.

Legal Information

SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

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This Item	P5607	93693	PHR1332
SAFC P8865 L-Proline	Sigma-Aldrich P5607 L-Proline	Supelco 93693 L-Proline	Supelco PHR1332 L-Proline
form crystalline powder	form powder	form -	form -
biological source non-animal source	biological source non-animal source	biological source -	biological source -
impurities endotoxin, heavy metals, residual solvents, tested	impurities endotoxin, tested	impurities -	impurities -
assay ≥98.5%	assay 98.5-101.0% dry basis	assay -	assay -
application(s) pharmaceutical (small molecule)	application(s) pharmaceutical (small molecule)	application(s) cleaning products cosmetics flavors and fragrances food and beverages personal care	application(s) pharmaceutical (small molecule)
technique(s) cell culture \| mammalian: suitable	technique(s) cell culture \| mammalian: suitable	technique(s) HPLC: suitable, gas chromatography (GC): suitable	technique(s) HPLC: suitable, gas chromatography (GC): suitable

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Storage Class

11 - Combustible Solids

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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