Skip to Content
Merck
All Photos(1)

Documents

P6641

Sigma-Aldrich

1,2-Diacyl-sn-glycero-3-phospho-L-serine solution

≥97%, from bovine brain, chloroform:methanol solution

Synonym(s):

3-sn-Phosphatidyl-L-serine, L-α-Phosphatidyl-L-serine, PS, Phosphatidylserine

Sign Into View Organizational & Contract Pricing


About This Item

UNSPSC Code:
51191904
NACRES:
NA.25

biological source

bovine brain

Assay

≥97%

form

chloroform:methanol solution

functional group

phospholipid

lipid type

phosphoglycerides

shipped in

dry ice

storage temp.

−20°C

Application


  • Electrophoretic Light Scattering and Electrochemical Impedance Spectroscopy Studies of Lipid Bilayers Modified by Cinnamic Acid and Its Hydroxyl Derivatives.: This study explores the modification of lipid bilayers, specifically focusing on the interactions between cinnamic acid derivatives and lipid structures, including 1,2-Diacyl-sn-glycero-3-phospho-ʟ-serine solutions. It employs electrophoretic light scattering and electrochemical impedance spectroscopy to elucidate the electrochemical properties and stability of these modified bilayers, highlighting their potential in biophysical and biochemical applications (Naumowicz et al., 2020).

  • Silica-based Monolithic Capillary Columns Modified by Liposomes for Characterization of Analyte-Liposome Interactions by Capillary Liquid Chromatography.: This research investigates the use of silica-based monolithic capillary columns modified with liposomes, including 1,2-Diacyl-sn-glycero-3-phospho-ʟ-serine, to study analyte-liposome interactions. The capillary liquid chromatography technique used in this study provides insights into the behavior of analytes within lipid environments, which is crucial for understanding membrane interactions and developing lipid-based delivery systems (Moravcová et al., 2013).

Biochem/physiol Actions

A slowly metabolized structural phospholipid found mainly in gray matter.

Caution

Solutions exposed to room temperature will decompose about 0.5% per day.

Analysis Note

Actual concentration given on label.

Signal Word

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Flam. Liq. 3 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 Oral - STOT SE 2 - STOT SE 3

Target Organs

Eyes,Central nervous system, Liver,Kidney, Respiratory system

Storage Class Code

3 - Flammable liquids

WGK

WGK 3

Flash Point(F)

80.1 °F - closed cup

Flash Point(C)

26.7 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Riccardo Provenzani et al.
PloS one, 13(4), e0195668-e0195668 (2018-04-12)
Protein kinase C (PKC) isoforms play a pivotal role in the regulation of numerous cellular functions, making them extensively studied and highly attractive drug targets. Utilizing the crystal structure of the PKCδ C1B domain, we have developed hydrophobic isophthalic acid
Kwang-jin Cho et al.
The Journal of biological chemistry, 287(52), 43573-43584 (2012-11-06)
Oncogenic mutant Ras is frequently expressed in human cancers, but no anti-Ras drugs have been developed. Since membrane association is essential for Ras biological activity, we developed a high content assay for inhibitors of Ras plasma membrane localization. We discovered
T I Lin et al.
Journal of virology, 75(8), 3647-3656 (2001-03-27)
The viral ion channel protein M2 supports the transit of influenza virus and its glycoproteins through acidic compartments of the cell. M2 conducts endosomal protons into the virion to initiate uncoating and, by equilibrating the pH at trans-Golgi membranes, preserves
Christine A McCary et al.
The Biochemical journal, 441(1), 189-198 (2011-09-22)
Vitamin E isoforms have opposing regulatory effects on leucocyte recruitment during inflammation. Furthermore, in vitro, vitamin E isoforms have opposing effects on leucocyte migration across endothelial cells by regulating VCAM (vascular cell-adhesion molecule)-1 activation of endothelial cell PKCα (protein kinase
Leonardo Almeida-Souza et al.
Cell, 174(2), 325-337 (2018-06-12)
Multiple proteins act co-operatively in mammalian clathrin-mediated endocytosis (CME) to generate endocytic vesicles from the plasma membrane. The principles controlling the activation and organization of the actin cytoskeleton during mammalian CME are, however, not fully understood. Here, we show that

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service