P3892

Poly-L-arginine hydrochloride

suitable for bioconjugations, Mol wt >70,000

• Synonym(s): L-Arginine homopolymer hydrochloride
• CAS Number: 26982-20-7
• UNSPSC Code: 12352209
• PubChem Substance ID: 24898466
• NACRES: NA.26
• MDL number: MFCD00166393

Properties

• Product Name: Poly-L-arginine hydrochloride, mol wt >70,000
• form: powder or solid
• Quality Segment: 200
• mol wt: >70,000
• technique(s): bioconjugation: suitable
• color: white to off-white
• storage temp.: −20°C
• SMILES string: Cl.NC(CCCNC(N)=N)C(O)=O
• InChI: 1S/C18H38N12O4.ClH/c19-10(4-1-7-26-16(20)21)13(31)29-11(5-2-8-27-17(22)23)14(32)30-12(15(33)34)6-3-9-28-18(24)25;/h10-12H,1-9,19H2,(H,29,31)(H,30,32)(H,33,34)(H4,20,21,26)(H4,22,23,27)(H4,24,25,28);1H/t10-,11-,12-;/m0./s1
• InChI key: PQEISBBDIRAKGR-LFELFHSZSA-N

Description

Application

Poly-L-arginine hydrochloride has been used:

• as polyelectrolyte solution in the synthesis of biodegradable capsules
• as layer constituent, in the preparation of layer by layer (LbL) assembly of multilayer biodegradable shells
• in assay for the determination of binding activity of C-reactive protein for polycationic ligands

Biochem/physiol Actions

Poly-L-arginine (PLA) possesses anti-bacterial activity. It has a greater capacity to enhance membrane permeability. PLA at lower concentration enhances cell proliferation and at higher concentration acts as antiproliferative agent.

Analysis Note

Contains 3% or less ornithine residue by TLC.

Molecular weight based on viscosity of precursor poly-L-ornithine.

Other Notes

For additional technical information on polyamino acids please visit the Polyamino acid FAQ resource.

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type N95 (US)