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Merck

P2533

Poly-L-ornithine hydrochloride

suitable for ligand binding assays, Mol wt 15,000-30,000

Synonym(s):

L-Ornithine homopolymer hydrochloride

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About This Item

CAS Number:
UNSPSC Code:
12352209
PubChem Substance ID:
NACRES:
NA.26
MDL number:
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Product Name

Poly-L-ornithine hydrochloride, mol wt 15,000-30,000

form

powder or solid

Quality Segment

mol wt

15,000-30,000

technique(s)

ligand binding assay: suitable

color

white to off-white

storage temp.

−20°C

SMILES string

Cl.NCCCC(N)C(O)=O

InChI key

GGTYBZJRPHEQDG-UHFFFAOYSA-N

Application

Poly-L-ornithine hydrochloride has been used as a substrate analog of acetyl-poly-L-lysine to study substrate binding and catalysis of the NAD-dependent protein deacetylase Hst2. It has been used to bind alginate-polycation-alginate (APA) microcapsules.

Biochem/physiol Actions

Poly-L-ornithine is a polycationic synthetic amino acid polymer. It boosts nasal absorption of hydrophilic macromolecular drugs. Poly-L-ornithine is a specialized coating that acts as a charge modifier.

Analysis Note

Molecular weight based on viscosity.

Other Notes

For additional technical information on polyamino acids please visit the Polyamino acid FAQ resource.


Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)



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