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2-O-(p-Nitrophenyl)-α-D-N-acetylneuraminic acid

Name: 2-O-(p-Nitrophenyl)-&#945;-<SC>D</SC>-N-acetylneuraminic acid
Brand: SIGMA

chromogenic, ≥95%, powder

Synonym(s):

PNP-a-NeuNAc

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About This Item

Empirical Formula (Hill Notation):

C₁₇H₂₂N₂O₁₁

CAS Number:

26112-88-9

Molecular Weight:

430.36

UNSPSC Code:

12352204

PubChem Substance ID:

24897497

NACRES:

NA.32

MDL number:

MFCD00132944

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Properties

Product Name

2-O-(p-Nitrophenyl)-α-D-N-acetylneuraminic acid, ≥95%

Quality Segment

200

assay

≥95%

form

powder

impurities

~0.5% free p-nitrophenol

solubility

methanol: 25 mg/mL, clear, colorless to faintly yellow

shipped in

wet ice

storage temp.

−20°C

SMILES string

CC(=O)NC1C(O)CC(OC1C(O)C(O)CO)(Oc2ccc(cc2)N(=O)=O)C(O)=O

InChI

1S/C17H22N2O11/c1-8(21)18-13-11(22)6-17(16(25)26,30-15(13)14(24)12(23)7-20)29-10-4-2-9(3-5-10)19(27)28/h2-5,11-15,20,22-24H,6-7H2,1H3,(H,18,21)(H,25,26)

InChI key

OICUZSPXIJAAEA-UHFFFAOYSA-N

Description

Application

2-O-(p-Nitrophenyl)-α-D-N-acetylneuraminic acid may be used as a substrate to measure sialidase enzyme activity.

Biochem/physiol Actions

2-O-(p-Nitrophenyl)-α-D-N-acetylneuraminic acid serves as a sialyl donor in enzyme-catalyzed trans-sialylation.

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This Item	B4666	N6133	S1899
Sigma-Aldrich N1516 2-O-(p-Nitrophenyl)-α-D-N-acetylneuraminic acid	Sigma-Aldrich B4666 5-Bromo-4-chloro-3-indolyl α-D-N-acetylneuraminic acid sodium salt	Sigma-Aldrich N6133 4-Nitrophenyl N,N′-diacetyl-β-D-chitobioside	Sigma-Aldrich S1899 N-Succinyl-Gly-Gly-Phe-p-nitroanilide
description ≥95%	description ≥90%	description ≥99% (TLC)	description protease substrate
assay ≥95%	assay ≥90%	assay ≥99% (TLC)	assay ≥98% (TLC)
solubility methanol: 25 mg/mL, clear, colorless to faintly yellow	solubility water: 50 mg/mL, clear, colorless to faintly yellow	solubility DMF: 24.50-25.50 mg/mL	solubility acetic acid: 20 mg/mL, clear, colorless to faintly yellow
Quality Level 200	Quality Level 200	Quality Level 200	Quality Level 200
form powder	form powder	form powder	form powder
shipped in wet ice	shipped in -	shipped in -	shipped in -
storage temp. −20°C	storage temp. −20°C	storage temp. 2-8°C	storage temp. −20°C

pictograms

GHS06,GHS08

signalword

Danger

hcodes

H301 + H311 + H331,H315,H319,H335,H351

pcodes

P202 - P280 - P301 + P310 - P302 + P352 + P312 - P304 + P340 + P311 - P305 + P351 + P338

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Carc. 2 - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

ppe

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges

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