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M7439

Methyl-β-cyclodextrin

Synonym(s):

Methyl-beta-cyclodextrin

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About This Item

CAS Number:
UNSPSC Code:
12352201
NACRES:
NA.22
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form

powder

Quality Segment

impurities

<10.0% water (Karl Fischer)

color

white

mp

180-182 °C (lit.)

application(s)

advanced drug delivery

SMILES string

O1C2OC(C(OC3OC(C(OC4OC(C(OC5OC(C(OC6OC(C(OC7OC(C(OC8OC(C1C(C8OC)O)COC)C(C7OC)O)COC)C(C6OC)O)COC)C(C5OC)O)COC)C(C4OC)O)COC)C(C3OC)O)COC)C(C2OC)O)COC

InChI

1S/C56H98O35/c1-64-15-22-36-29(57)43(71-8)50(78-22)86-37-23(16-65-2)80-52(45(73-10)30(37)58)88-39-25(18-67-4)82-54(47(75-12)32(39)60)90-41-27(20-69-6)84-56(49(77-14)34(41)62)91-42-28(21-70-7)83-55(48(76-13)35(42)63)89-40-26(19-68-5)81-53(46(74-11)33(40)61)87-38-24(17-66-3)79-51(85-36)44(72-9)31(38)59/h22-63H,15-21H2,1-14H3

InChI key

QGKBSGBYSPTPKJ-UHFFFAOYSA-N

General description

Methyl-β-cyclodextrin is a small cyclic heptasaccharide.

Application

Methyl-β-cyclodextrin has been used as a cholesterol chelator:
  • to study its effects on mice cardiomyocytes
  • to study its effects on human corneal stromal fibroblasts
  • to study its effects on the junctophilin-2 (JPH2) pool

Biochem/physiol Actions

Methyl-β-cyclodextrin participates in increasing the permeability of cells. It also plays a role in depolymerizing the actin cytoskeleton in cells. Methyl-β-cyclodextrin is involved in attracting cholesterol from the plasma. It participates in activating extracellular receptor kinase in certain cells.

Other Notes

To gain a comprehensive understanding of our extensive range of Polysaccharides for your research, we encourage you to visit our Carbohydrates Category page.

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This Item
779776332615C4555
description

-

description

Wacker Chemie AG, ≥95.0% cyclodextrin basis (calculated)

description

average Mn 1310

description

powder, BioReagent, suitable for cell culture

Quality Level

200

Quality Level

100

Quality Level

100

Quality Level

300

form

powder

form

powder

form

powder

form

powder

color

white

color

-

color

white

color

-

impurities

<10.0% water (Karl Fischer)

impurities

≤0.2% unsubstituted cyclodextrin, ≤2% chloride, ≤0.2% volatile organics

impurities

-

impurities

-

mp

180-182 °C (lit.)

mp

180-182 °C (lit.)

mp

180-182 °C (lit.)

mp

180-182 °C (lit.)

application(s)

advanced drug delivery

application(s)

-

application(s)

advanced drug delivery

application(s)

-


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Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

368.6 °F

flash_point_c

187 °C

ppe

Eyeshields, Gloves, type N95 (US)



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Questions

  1. What is the molecular weight of product M7439-1G? It is not available online or on the delivered bottle.

    1 answer
    1. The molecular weight of this product varies based on the average number of methyl groups per glucose residue, which is reported on the Certificate of Analysis. The data is presented as follows: 1.6, 1292; 1.7, 1302; 1.8, 1311; 1.9, 1320; 2.0, 1331; 2.1, 1341.

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