This product is an MQ Level 200 and suitable for research use only. It would not be suitable for the production of a pharmaceutical product. Currently, there is no L-(?)-Malic acid offered that is suitable for this application.
M7397
L-(−)-Malic acid
suitable for cell culture, BioReagent, suitable for insect cell culture
Synonym(s):
(S)-(−)-2-Hydroxysuccinic acid, L-Hydroxybutanedioic acid
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About This Item
Linear Formula:
HO2CCH2CH(OH)CO2H
CAS Number:
Molecular Weight:
134.09
UNSPSC Code:
12352205
NACRES:
NA.75
PubChem Substance ID:
EC Number:
202-601-5
Beilstein/REAXYS Number:
1723541
MDL number:
Assay:
≥95% (titration)
Form:
powder
Pricing and availability is not currently available.
biological source
microbial
Quality Segment
product line
BioReagent
assay
≥95% (titration)
form
powder
technique(s)
cell culture | insect: suitable, cell culture | mammalian: suitable
mp
101-103 °C (lit.)
solubility
water: 100 mg/mL, clear to slightly hazy, colorless
SMILES string
O[C@@H](CC(O)=O)C(O)=O
InChI
1S/C4H6O5/c5-2(4(8)9)1-3(6)7/h2,5H,1H2,(H,6,7)(H,8,9)/t2-/m0/s1
InChI key
BJEPYKJPYRNKOW-REOHCLBHSA-N
General description
Malic acid is used as a component of insect tissue culture. It is also useful as an acidulant in soft drinks, jams, fruit and vegetable juices.
Application
Malic acid has been used:
- to induce basal respiration in mitochondrial cell culture[1]
- to measure the mitochondrial ETC (electron transport chain) activity
- as a component of mitochondrial substrate stock
Biochem/physiol Actions
Malic acid is a part of cellular metabolism. Its application is recognized in pharmaceutics. It is useful in the treatment of hepatic malfunctioning, effective against hyper-ammonemia. It is used as a part of amino acid infusion. Malic acid also serves as a nanomedicine in the treatment of brain neurological disorders. A TCA (Krebs cycle) intermediate and partner in the malic acid aspartate shuttle.
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This Item | |||
|---|---|---|---|
| assay ≥95% (titration) | assay 97% | assay - | assay ≥95% |
| Quality Level 200 | Quality Level 200 | Quality Level 300 | Quality Level 200 |
| form powder | form powder | form - | form powder |
| solubility water: 100 mg/mL, clear to slightly hazy, colorless | solubility - | solubility - | solubility H2O: 0.5 M at 20 °C, clear, colorless |
| mp 101-103 °C (lit.) | mp 101-103 °C (lit.) | mp 101-103 °C (lit.) | mp 101-103 °C (lit.) |
| biological source microbial | biological source - | biological source - | biological source - |
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signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2
Storage Class
11 - Combustible Solids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
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Global Trade Item Number
| SKU | GTIN |
|---|---|
| M7397-100G | 04061834061953 |
| M7397-500G | 04061834061977 |
| M7397-25G | 04061834061960 |
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What is the quality level of this product? (I would like to use it as an ingredient in a medium to cultivate cells to be used as starting material for a pharmaceutical product, do you have other suggestions?)
1 answer-
Helpful?
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