L7140

S-Lactoylglutathione

≥90% (TLC)

• Synonym(s): SLG
• Empirical Formula (Hill Notation): C₁₃H₂₁N₃O₈S
• CAS Number: 54398-03-7
• Molecular Weight: 379.39
• NACRES: NA.26
• PubChem Substance ID: 24896452
• UNSPSC Code: 12352209
• MDL number: MFCD06858227

Properties

• assay: ≥90% (TLC)
• form: powder
• color: white
• application(s): detection
• storage temp.: −20°C
• SMILES string: C[C@H](O)C(=O)SC[C@H](NC(=O)CC[C@H](N)C(O)=O)C(=O)NCC(O)=O
• InChI: 1S/C13H21N3O8S/c1-6(17)13(24)25-5-8(11(21)15-4-10(19)20)16-9(18)3-2-7(14)12(22)23/h6-8,17H,2-5,14H2,1H3,(H,15,21)(H,16,18)(H,19,20)(H,22,23)/t6-,7-,8-/m0/s1
• InChI key: VDYDCVUWILIYQF-FXQIFTODSA-N

Description

General description

Suitable for use as a substrate for glyoxalase II.

Application

• Untargeted metabolomics provide new insights into the implication of Lactobacillus helveticus strains isolated from natural whey starter in methylglyoxal-mediated browning.: This research utilizes untargeted metabolomics to investigate the role of S-lactoylglutathione in the browning reaction mediated by methylglyoxal, highlighting its implications in food processing and safety (Galimberti S et al., 2023).


• Multi-omics analysis reveals the molecular regulatory network underlying the prevention of Lactiplantibacillus plantarum against LPS-induced salpingitis in laying hens.: The study identifies the role of S-lactoylglutathione in the regulatory network that prevents LPS-induced salpingitis, emphasizing its importance in avian health and biotechnology applications (Song D et al., 2023).


• Analysis of Glyoxal- and Methylglyoxal-Derived Advanced Glycation End Products during Grilling of Porcine Meat.: This study examines the formation of advanced glycation end products (AGEs) derived from glyoxal and methylglyoxal, focusing on the role of S-lactoylglutathione in mitigating these reactions during meat grilling (Eggen MD et al., 2021).

Biochem/physiol Actions

S-Lactoylglutathione (SLG) is used to study the glutathione-dependent glyoxalase system and KefGB potassium efflux pump in bacteria and plants. S-Lactoylglutathione may also be used to study the inhibition of de novo pyrimidine synthesis in cancer.

Safety Information

• Pictograms: GHS07
• Signal Word: Warning
• Hazard Codes: H315,H319,H335
• Precautionary Statements: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Target Organs: Respiratory system
• Storage Class: 11 - Combustible Solids
• WGK: WGK 3
• PPE (personal protective equipment): dust mask type N95 (US), Eyeshields, Gloves