L0906
L-α-Lysophosphatidylcholine from Glycine max (soybean)
≥99%, lyophilized powder
Synonym(s):
1-Acyl-sn-glycero-3-phosphocholine, L-α-Lysolecithin
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About This Item
Pricing and availability is not currently available.
biological source
soybean
Quality Segment
description
zwitterionic
assay
≥99%
form
lyophilized powder
functional group
phospholipid
lipid type
phosphoglycerides
shipped in
ambient
storage temp.
−20°C
Biochem/physiol Actions
Lysophosphatidylcholine is a major component of oxidized low density lipoproteins, and has been implicated in various inflammatory reactions, including atherosclerosis. It is used to demyelinate spinal neurons and study the processes underlying remyelination. It activates protein kinase C, p38 MAP kinase, p42 MAP Kinase, and the jun kinase (JNK) pathway, and stimulates transcription of c-jun.
Lysophosphatidylcholine is a major component of oxidized low density lipoproteins, and has been implicated in various inflammatory reactions, including atherosclerosis. It is used to demyelinate spinal neurons and study the processes underlying remyelination. It activates protein kinase C, p38 MAP kinase, p42 MAP Kinase, and the jun kinase (JNK) pathway, and stimulates transcription of c-jun. Lysophosphatidylcholine accumulates during cardiac ischemia and may induce arrhythmias by uncoupling gap junction communication, and increase ischemic damage by enhancing Na+ loading in cardiac myocytes. It also activates TREK1, TREK2 and TRAAK K+ channels.
Packaging
Packaged under Argon.
Preparation Note
Prepared by the action of phospholipase A on soybean L-α-phosphatidylcholine (P 6263).
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This Item | |||
|---|---|---|---|
| description ≥99%, lyophilized powder | description Type IV, ≥98% (TLC), lyophilized powder | description ≥96% | description from soybean, ≥98.0% (10 mg phospholipid per ml CHCl3, TLC) |
| assay ≥99% | assay ≥98% (TLC) | assay ≥96% | assay ≥98.0% (10 mg phospholipid per ml CHCl3, TLC) |
| form lyophilized powder | form lyophilized powder | form powder | form - |
| storage temp. −20°C | storage temp. −20°C | storage temp. −20°C | storage temp. −20°C |
| Quality Level 200 | Quality Level 200 | Quality Level 200 | Quality Level 100 |
| description zwitterionic | description - | description - | description zwitterionic |
| biological source soybean | biological source soybean | biological source soybean | biological source soybean |
Storage Class
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
PPE (personal protective equipment)
Eyeshields, Gloves, type N95 (US)
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