K3519

KRM-III

≥98% (HPLC)

• Synonym(s): 1,3-Dihydro-1,4-diphenyl-2H-imidazole-2-thione
• Empirical Formula (Hill Notation): C₁₅H₁₂N₂S
• CAS Number: 79220-94-3
• Molecular Weight: 252.33
• NACRES: NA.77
• PubChem Substance ID: 329817137
• UNSPSC Code: 12352200
• MDL number: MFCD02712628
• Assay: ≥98% (HPLC)
• Form: powder

Properties

• Quality Segment: 100
• assay: ≥98% (HPLC)
• form: powder
• color: light yellow to light tan
• solubility: DMSO: soluble ≥20 mg/mL
• storage temp.: 2-8°C
• SMILES string: S=C1NC(=CN1c2ccccc2)c3ccccc3
• InChI: 1S/C15H12N2S/c18-15-16-14(12-7-3-1-4-8-12)11-17(15)13-9-5-2-6-10-13/h1-11H,(H,16,18)
• InChI key: QKOAQVKXZJFMET-UHFFFAOYSA-N

Description

Biochem/physiol Actions

KRM-III is an inhibitor of T cell antigen receptor (TCR), an inhibitor of phorbol myristate acetate (PMA) /ionomycin-induced nuclear factor of activated T cells (NFAT) activation and T cell proliferation.

Safety Information

• pictograms: GHS07
• signalword: Warning
• hcodes: H319
• pcodes: P264 - P280 - P305 + P351 + P338 - P337 + P313
• Hazard Classifications: Eye Irrit. 2
• Storage Class: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable