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I6891

Sigma-Aldrich

H-7

Synonym(s):

1-(5-Isoquinolinesulfonyl)-2-methylpiperazine, Isoquinoline-5-sulfonic 2-methyl-1-piperazide

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About This Item

Empirical Formula (Hill Notation):
C14H17N3O2S
CAS Number:
84477-87-2
Molecular Weight:
291.37
Beilstein:
5482740
MDL number:
MFCD00063403
UNSPSC Code:
12352200
PubChem Substance ID:
24896097
NACRES:
NA.77

Assay

≥98% (HPLC)

form

powder

mp

114 °C

solubility

ethanol: 20 mg/mL
1 M HCl: 5 mg/mL

storage temp.

2-8°C

SMILES string

CC1CNCCN1S(=O)(=O)c2cccc3cnccc23

InChI

1S/C14H17N3O2S/c1-11-9-16-7-8-17(11)20(18,19)14-4-2-3-12-10-15-6-5-13(12)14/h2-6,10-11,16H,7-9H2,1H3

InChI key

BDVFVCGFMNCYPV-UHFFFAOYSA-N

Gene Information

human ... CALCRL(10203)
rat ... Calcrl(25029)

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Biochem/physiol Actions

Inhibitor of cyclic nucleotide dependent protein kinase (PKA) and protein kinase C.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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