I6783

Isopimaric Acid

≥98% (GC), potassium (BK) channel oepner, powder

• Empirical Formula (Hill Notation): C₂₀H₃₀O₂
• CAS Number: 5835-26-7
• Molecular Weight: 302.45
• UNSPSC Code: 12352106
• PubChem Substance ID: 24724518
• NACRES: NA.77
• MDL number: MFCD04113116
• Assay: ≥98% (GC)
• Form: powder

Properties

• Product Name: Isopimaric Acid, ≥98% (GC), powder
• Quality Segment: 100
• assay: ≥98% (GC)
• form: powder
• color: white
• solubility: DMSO: 25 mg/mL
• storage temp.: −20°C
• SMILES string: [H][C@]12CC[C@@](C)(CC1=CC[C@@]3([H])[C@@](C)(CCC[C@]23C)C(O)=O)C=C
• InChI: 1S/C20H30O2/c1-5-18(2)12-9-15-14(13-18)7-8-16-19(15,3)10-6-11-20(16,4)17(21)22/h5,7,15-16H,1,6,8-13H2,2-4H3,(H,21,22)/t15-,16+,18-,19+,20+/m0/s1
• InChI key: MXYATHGRPJZBNA-KRFUXDQASA-N

Description

General description

Isopimaric acid, a resin acid produced by conifer trees, is a tricyclic diterpene compound. High levels of isopimaric acid in the hepatocytes of the rainbow trout may impair calcium signalling machinery. Isopimaric acid is a potential big potassium (BK) channel opener.

Biochem/physiol Actions

Potent opener of large conductance calcium activated K⁺ (BK) channels.

Features and Benefits

This compound is featured on the Potassium Channels page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Safety Information

• pictograms: GHS09
• signalword: Warning
• hcodes: H400
• pcodes: P273
• Hazard Classifications: Aquatic Acute 1
• Storage Class: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type N95 (US)